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Content archived on 2024-06-18

Molecular and cellular heterogeneity of tumour stem cells in human glioblastoma

Objective

"Despite the emergence of new targeted therapies, there is still no curative treatment for many human cancers. Through the need for the best combination and solution, a new theory has suggested that cancer is as a stem cell-driven disease and a growing body of evidence has supported this hypothesis.
In this context, the applicant proposes to investigate the biological function and complexity of the so called ""tumour stem cells"" in the most devastating human brain cancer, i.e. glioblastoma. Cells isolated from different areas of the same tumour will be characterised at genotypic and phenotypic level. This study will increase our knowledge about brain tumour biology and will shed new lights on the function of tumour stem cells in human glioblastoma.
The project will be carried out at the Department of Clinical Neurosciences of the University of Cambridge in an international and stimulating institute that is ranked first of all the UK’s top medical schools in both teaching and research and is one of the top Universities in the world. The applicant has a strong background in gene therapy, neural stem cell and brain tumours and will receive scientific and non-scientific training ranging from acquisition of novel scientific methodology for the development of the project to new skills for career development and will be encouraged to establish local and international collaborations. Complimentary activities will be provided by the University staff, the Human Resource Division and the Career Service.
Considering past achievements and potential of the applicant, it is reasonable to envisage a successful post-doc career at the University of Cambridge. In this view, the Marie Curie Intra-European fellowship will substantially foster the applicant to emerge in the international community of scientists working on cancer and in the future to apply as junior group leader in the country of origin."

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2010-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
EU contribution
€ 200 549,60
Address
TRINITY LANE THE OLD SCHOOLS
CB2 1TN CAMBRIDGE
United Kingdom

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Region
East of England East Anglia Cambridgeshire CC
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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