Objective
Over the last decade, considerable progress has been achieved in the treatment of both traumatic skin injury, such as severe burns, or the treatment of chronic soft tissue injury, such as chronic ulcers, by the use of tissue engineering scaffolds within which either natural, or stem cell based tissue regeneration can take place. One of the problems of using scaffolds in hospital is bacterial infection, which tends to start at a focal point, and spread across the wound bed and by the time this is obvious enough to see, the infection is well-progressed and difficult to eradicate with either antibiotics, or silver or iodine dressings.
This proposal seeks to develop a novel material, smart cryogels, capable of responding to specific “signalling molecules” released either by bacteria or as a product of the immune response; to be used as wound dressings, and as tissue engineering scaffolds. The strategy proposed in the proposal is to secure the antimicrobial agent inside the polymer matrix controlling its release until it is needed. This allows targeting of the areas affected by infection, with antimicrobial agents, thus performing micro-point treatment. The fast specific response also allows release of the antimicrobial agent at the first sign of bacterial colonisation, providing earlier treatment, preventing infection and bacterial spreading, thus providing better treatment. The ability to treat infection at an earlier stage will significantly improve the healing process, providing better treatment and reduction of cost.
The potential benefits of the project are very high, as the novel smart macroporous materials which will be developed have clear clinical and commercial potential as delivery materials for diverse applications in medicine, such as biomaterials, sensing/diagnosis devises and drug delivery systems.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences basic medicine immunology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- natural sciences chemical sciences inorganic chemistry halogens
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-RG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BN2 4AT Brighton
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.