Objective
"This project aims at the advancement on fundamental knowledge on the evolution of fish cytokines and at the development of vaccination strategies against highly cytopathic virus of carp, taking as studying model SVCV. Worldwide, common carp is the most cultured fish species for food consumption with a value of US$20 billion. Koi carp are ornamental varieties of common carp and individual fish may exceed US$100.000 in value, making koi the most expensive fish in the world. However, virus infections are causing substantial economic losses in this market so there is an urgent need for the development of safe and efficacious vaccines that induce protective memory but, at present, virtually nothing is known regarding the immune response of carp to these viruses. The first aim of this project is the characterization of the immune responses of carp to SVCV infections. Specially, the study of those cytokines which are crucial for the development of protective cellular immune responses against viral infections, such as interferon alpha-beta (INFab) which has already considered to be a putative signal-3 cytokine (required for optimal programming for survival, effector function and memory of CD8+ T cells). Therefore, the second aim is the characterization of bioactivity of carp-INFab which we hypothesize can be used as a molecular adjuvant to optimize vaccination against SVCV. The third aim is the development of vaccination protocols based on protective immunity induced by a new generation vaccine, a ‘INFab-adjuvated’ DNA vaccine against SVCV. The combined use of fundamental and applied approaches will provide the scientific rationale necessary for an improved development of safe and efficacious vaccines against deadly viruses of carp."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
6708 PB Wageningen
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.