Objective
Human iPS cell therapy for Spinal Cord Injury with Acronym: “Human iPS in SCI”
Our overall aim is to develop a clinically safe and effective neural cell therapy, combining novel biomaterials and human neural progenitor cells, to improve functional outcome after spinal cord injury (SCI). We have the unique possibility to compare neuro-rescue potentials of human induced pluripotent stem (iPS) cells and their neural progeny, with that of human neural precursor cells from the already formed spinal cord.
The questions raised and studied in the present research program are unique with the introduction of human iPS cells and bioresorbable hydrogels. It offers future autologous transplantation procedures and thereby no immunological and reduced ethical considerations. If we manage, we can make patient-specific cell preparations to counteract the secondary degeneration after SCI. The project is of high relevance for clinical introduction of neural cell therapy after SCI, as well as other nervous system lesions.
Our proposed project will significantly contribute and add novel and multidisciplinary competencies to my profile as research fellow, developing my skills as a valid and independent European researcher. The cultural exchange with Karolinska Institutet will allow me to gain knowledge and skills in human neural stem cell, iPS techniques, SCI in vitro and in vivo models as well as in the field of biomaterial engineering. In addition, my genuine geographical move to Karolinska Institutet, Stockholm to perform this project, offers me to join, and add knowledge to, the European research community in developing effective future cell therapies for neurodegenerative and traumatic nervous system lesions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences neurobiology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences clinical medicine transplantation
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
171 77 STOCKHOLM
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.