OLEAginous yeast platforms for FINE chemicals

Objective

The academic and industrial partners engaged in the OLEFINE project have the joint vision of demonstrating the techno-economic viability and sustainability of biological production of insect pheromones for use as safe and environmentally friendly insecticide substitutes. Biological production of cheaper pheromones will be a market disrupting technology that will
allow rapid expansion of pheromone-based pest management products. The partners behind OLEFINE have developed a novel technology for biological production of pheromones using oleaginous yeast cell factories, however the strains, fermentation, and downstream process need to be further optimized to bring the technology to the market.
OLEFINE aims to optimize, validate, and commercialize biotech process for production of high-added-value chemicals
(insect pheromones) for use as non-toxic insecticide replacements. Cost-efficiency and sustainability of the current process
will be lifted in this project by optimizing the yeast biocatalyst and by employing innovative fermentation and downstream
processing with cascading of resources. The production cost will be reduced by at least 75% in relation to the current state-of-the-art. The process will be validated in industrial environment for two pheromones (TRL7), techno-economic viability will be estimated and business plans will be prepared. The environmental impact and sustainability will be evaluated by full Life Cycle Analysis. The technology will be brought to the market by OLEFINE industrial partners post project.
In summary, OLEFINE will bring new sustainable high-value chemicals to the market and create new business opportunities and jobs in European biotech sector, which is in line with the challenge of the topic.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• agricultural sciencesagriculture, forestry, and fisheriesagricultureagronomyplant protection
• agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturevegetable growing
• natural scienceschemical sciencescatalysisbiocatalysis
• natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes
• engineering and technologyindustrial biotechnologybioprocessing technologiesfermentation

Programme(s)

• H2020-EU.2.1.4. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology Main Programme

Topic(s)

• BIOTEC-06-2017 - Optimisation of biocatalysis and downstream processing for the sustainable production of high value-added platform chemicals

Funding Scheme

Coordinator

Participants (9)