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Gold nanoparticle films for universal biosensors

Objective

The current biosensing marker for healthcare and environmental applications is dominated by laboratory instrumentation that is bulky, time consuming, and expensive and requires well-equipped laboratories and skilled personnel. Many essential applications, such as disease diagnostics (e.g. hepatitis B, tuberculosis, HIV) and water quality monitoring (e.g. pathogens, heavy metals, toxins), are often neglected due to economic reasons, causing millions of deaths globally.
The most significant challenges facing biosensors are their fabrication and instrumentation costs, insensitivity, and low-throughput detection. One technique capable of tackling these challenges is localised surface plasmon resonance which has demonstrated the potential to deliver cost-effective hand-held point-of-care devices with rapid, multi-analyte detection. To date, this potential has been limited by the available techniques for fabricating feasible nanoscale sensors.
I have chosen a world-recognized research centre, the Leibniz Institute of Photonic Technology in Germany, as my host institution to develop my MSCA under the supervision of an excellent mentor in nanobiophotonics, where I will be trained in advanced techniques in nanophotonics. The acquired skills in combination with my own knowledge will perfectly match for developing a novel nanofabrication technique to deliver affordable and versatile sensors based on a 2D array of well-ordered and dense gold nanoparticles - a unique blend of interdisciplinary methods with the potential to rival lithography techniques but at a fraction of their costs. Precise control over nanostructured dimensions will allow me to tune the sensor for biosensing applications. Microarray biofunctionalisation of the sensor will demonstrate multiplexed detection of pathogens (DNA), disease biomarkers (proteins), and heavy metals and will pave the way for improved healthcare and environmental screening, where test availability, speed, and cost play a decisive role.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2022-PF-01

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Coordinator

LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 173 847,36
Address
Albert Einstein strasse 9
07745 Jena
Germany

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Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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