Objective
Incorporating biomolecules as integral parts of computational systems represents a frontier challenge in bio and nanotechnology. Using DNA to store digital data is an attractive alternative to conventional information technologies due to its high information density and long lifetime. However, developing an adequate DNA storage medium remains a significant challenge in permitting the safe archival and retrieval of oligonucleotides.
TextaDNA introduces polymer fibres as a novel approach to encapsulating and retrieving information-carrying oligonucleotides. We will develop a complete DNA storage workflow, encoding digital information into DNA base sequences and optimising oligonucleotide synthesis and encapsulation in polymer nano and microfibres. The project is led by nanoGUNE, a nanotechnology research centre, and partners with Eurofins, a leading European company specialising in state-of-art oligo synthesis and next-generation sequencing. We will design next-generation sequencing assays to automate the DNA digital storage readout retrieved from fibres. The enhanced oligo synthesis and sequencing strategies that, TextaDNA will develop are of fundamental interest in the path toward broader use of DNA digital storage, increasing synthesis speed and length of oligos and reducing costs. The consortium will create the conditions for encapsulating oligonucleotides inside polymer fibres and methods to retrieve them. We will establish efficient methods of synthesising oligonucleotides going beyond state-of-art phosphorodiamidate chemistry while ensuring their stability. Further, TextaDNA will also explore ways of incorporating sequencing technologies into reading digital data stored in oligonucleotide pools and expand the data storage capabilities of DNA.
TextaDNA will add to the European leadership in DNA data digital storage by leveraging oligo synthesis and sequencing with nanotechnology to build DNA digital storage materials.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules
- engineering and technology nanotechnology
- natural sciences chemical sciences polymer sciences
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-PATHFINDERCHALLENGES-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
20018 San Sebastian
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.