Project description
Revealing extra virgin olive oil’s health benefits
The Mediterranean Diet (MD) heavily relies on olive oil, particularly Extra Virgin Olive Oil (EVOO), for its health benefits. However, the full potential of EVOO's beneficial properties, specifically its phenolic compounds (PCs), is not fully realised due to potential loss during food processing. This leads to diminished health benefits, such as reduced protection against oxidative damage to blood lipids and lessened inhibition of pro-oxidant species formation. Supported by the Marie Skłodowska-Curie Actions (MSCA) programme, the Phenols4Health project aims to assess the transfer of PCs into various foods cooked with EVOO and their ability to inhibit dietary advanced glycation end-products (dAGEs). It will use advanced liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). This study offers potential economic benefits to the olive oil industry.
Objective
Olive oil is the main fat source in the Mediterranean Diet (MD). The healthy properties of extra virgin olive oil (EVOO) are associated with a balanced composition between major and minor compounds. Among the minor fraction, phenolic compounds (PCs) stand out in terms of their health promoting properties. PCs are responsible for the only specific health claim for olive oil, recognized by the European Food Safety Authority (EFSA), indicating that PCs in olive oil contribute to the protection of blood lipids against oxidative damage. Furthermore, due to their antioxidant capability, PCs are anticipated to exert inhibitory effects on the formation of pro-oxidant species, including advanced glycation end-products (AGEs), which play a pivotal role in oxidative stress and inflammation-related pathologies. Phenols4Health aims to elucidate the health benefits of foods processed in EVOO through the transference of PCs and their potential to inhibit the formation of dietary AGEs (dAGEs). A comprehensive investigation will be conducted to assess the transference of EVOOs' PCs into foods of diverse compositions. This proposal will also explore the influence of the PCs' profile in blocking the formation of AGEs in foods processed with EVOO. Finally, the study will evaluate the profile of AGEs in serum samples collected from individuals adhering to a MD supplemented with EVOO and a low-fat diet. The methodology required for Phenols4Health is based on the use of liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) for determination of the targeted species. The outcomes of this proposal hold the potential to make a profound impact at scientific, societal, and economic levels. By advancing the understanding of EVOO's health-enhancing properties and its role in inhibiting the formation of dAGEs, Phenols4Health will contribute to food science, nutrition, chemistry, and health fields, while fostering economic opportunities within the olive oil industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
This project's classification has been validated by the project's team.
- engineering and technology other engineering and technologies food technology
- natural sciences biological sciences biochemistry biomolecules lipids
- medical and health sciences health sciences nutrition
- medical and health sciences basic medicine pathology
- natural sciences chemical sciences analytical chemistry mass spectrometry
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-PF-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
14005 CORDOBA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.