Objective
Cervical cancer, caused by human papillomavirus (HPV), is almost entirely preventable through prophylactic HPV vaccination. Many countries have yet to implement HPV vaccination programmes or are struggling to achieve high vaccine coverage. This presents a major challenge for meeting the World Health Organisation (WHO) cervical cancer elimination target, with 90% of 15 year-old girls being vaccinated against HPV by 2030. Originally licenced as multidose vaccines, WHO has recently recommended that countries can offer a single HPV vaccine dose to 9-20 year olds. The IMPROVE-HPV consortium, a partnership of research institutions in Tanzania, Nigeria, UK and Spain, will investigate barriers to HPV vaccine uptake and the impact and acceptability of new HPV vaccine delivery strategies to improve vaccine coverage and effectiveness and reduce hesitancy. The consortium builds on previous successful collaborations in HPV epidemiology and vaccine research and qualitative research on barriers and facilitators to vaccine uptake. Tanzania has a multidose HPV vaccination programme in girls but will change to a single dose regimen in 2024. A gender-neutral HPV vaccination strategy is currently being implemented in Tanzania as part of a large cluster-randomised trial. Nigeria is one of the first countries to introduce national HPV vaccination with a single dose. Using these opportunities, IMPROVE-HPV will evaluate vaccine effectiveness, uptake and the factors affecting acceptability of (1) HPV two-dose vaccination delivery in females, (2) introducing or changing to a single dose vaccine regimen (3) gender-neutral HPV vaccination, and will also (4) investigate factors influencing vaccine hesitancy, community engagement and perceptions of HPV vaccines. The workplan directly addresses effectiveness and uptake of different HPV vaccine deployment strategies through phase IV/implementation research and will inform policy decision making in sub-Saharan Africa for HPV vaccination programmes.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences public health epidemiology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences clinical medicine oncology cervical cancer
- medical and health sciences health sciences infectious diseases DNA viruses
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.1 - Health
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-JU-RIA - HORIZON JU Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-JU-GH-EDCTP3-2023-02-two-stage
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
08908 Hospitalet de Llobregat
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.