Objective
THERABOT pioneers a groundbreaking approach in the fight against cancer through the development of engineered biohybrid agents, iBots. These iBots represent a significant leap in bacterial cancer therapy (BCT), combining synthetic biology and nanotechnology to encapsulate therapeutic bacteria with protective polymeric coatings. This encapsulation aims to enhance the delivery and efficacy of bacteria to colonize tumor tissue, drastically reducing the adverse immune responses and systemic toxicity associated with traditional BCT. THERABOT's innovative strategy focuses on colorectal cancer, employing a multifaceted approach that includes the design of advanced intelligent biohybrids by programming iBots for targeted therapeutic action, and validating their effectiveness in vivo. Central to THERABOT's mission is its interdisciplinary and international consortium, comprising 12 members from 10 leading academic institutions and 2 SMEs across Europe (France, Spain and Sweden) and from non-EU countries (Japan, Argentina, Chile, Brazil and Thailand). This collaboration fosters a unique integration of diverse scientific disciplines, including bioengineering, immunology, material science and oncology, promoting the exchange of knowledge, techniques, and cultural perspectives, which is pivotal for addressing the complex challenges of developing a new cancer therapy. THERABOT not only emphasizes the scientific innovation but also prioritizes the training and career development of seconded staff, enhancing their research competencies and preparing them for future challenges in diverse fields. THERABOT's focus on developing accessible and patient-friendly cancer treatments, underscores its alignment with EU priorities in health and innovation. By redefining cancer treatment paradigms towards more precise, effective, and personalized approaches, our project aspires to have a lasting impact on society, improving patient outcomes, and contributing to the global fight against cancer.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- engineering and technology nanotechnology
- medical and health sciences basic medicine immunology
- engineering and technology materials engineering coating and films
- medical and health sciences clinical medicine oncology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-SE - HORIZON TMA MSCA Staff Exchanges
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2023-SE-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75654 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.