Objective
Chronic wounds associated with diabetes mellitus, such as diabetic foot ulcers (DFUs), are an enormous clinical concern, placing a
significant economic burden on patients and healthcare systems around the globe. Currently, 44–70% of patients with DFUs treated
with current commercial therapies remain unhealed. This can be attributed to factors such as bacterial infections and a limited
oxygen supply, which cause diabetic chronic wounds to often remain in the inflammatory phase for months. Prior research in wound
healing biomaterials has been devoted to improving the functionality, or bioactivity of wound dressings, by enhancing the healing
process and extending the dressing usage time. Addressing diabetic wound healing through such wound healing dressings remains
challenging. In particular, since integrating the need for biomaterials that can reduce oxidative stress, deliver oxygen, stimulate
angiogenesis, and limit pathogen colonization simultaneously. Our proposal, e-OXYGENATE, employs an interdisciplinary approach
across electronics, materials, and their physicochemical and biological properties to develop a multifunctional wound dressing
using Oxygen-generating biomaterials and antimicrobial agents, achieving sustained release for several days to combat wound
infections and overcome hypoxia. In additional, Photobiomodulation (PBM) element will be used to accelerate regeneration, reduce
pain and inflammation. Through a novel, tri-layered electronic patch (e-Patch) consisting of an Oxygen profile monitoring
system, a hydration and mechanical support layer, and a nano-O2 carrier embedded scaffold, we aim to simultaneously treat and
monitor the challenges of bacterial infection while regenerating skin damaged by hypoxia-associated wounds.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.4.1 - Widening participation and spreading excellence
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-WIDERA-2025-TALENTS-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
38039 Kayseri
Türkiye
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.