Micro- and Nanostructured Polysaccharide Interfaces

Objective

"Natural polysaccharides (PS) and their derivatives provide a huge variety of functional groups leading to a great number of different physicochemical properties. Therefore functional polysaccharides are promising for the coating of man-made materials such as polymer surfaces, glass or ceramics in order to increase their functionality or biocompatibility. An elegant way to obtain coatings of natural polysaccharides is shaping of trimethylsilylated PS derivatives and subsequent regeneration of these structures to the initial PS. The target of this study is to produce electrospun and spin coated polysaccharide coatings from blends of hydrophobic trimethylsilylated PS and other hydrophobic PS derivatives and to subsequently regenerate these structures to the PS with the initial (bio-)function. This will produce functional polysaccharide coatings with tunable micro- and nanofibrous structures on a variety of materials. The influence of the structure and PS composition of these coatings on the physicochemical properties will be determined by surface analytical tools (Contact Angle Measurements, X-ray Photoelectronspectroscopy). The biocompatibility of the materials will be evaluated by extended protein adsorption studies with a quartz crystal microbalance. The regeneration process from trimethylsilylated PS will it further allow to introduce micropatterns on the PS surface coatings by lithographic methods. Spatially separated regeneration of the PS derivative coatings will produce patterns of electrospun or spin coated functional PS on substrates surrounded by non-regenerated hydrophobic PS derivatives. With the approaches described in this proposal, a vast number of tunable functional polysaccharide interface will be produced which will have potential applications as anti fouling coatings, as wound dressing material, as (bio-)sensor support, as low fouling functional filter webs or as biocompatible cell scaffolds in medicine."

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• natural sciences chemical sciences polymer sciences
• engineering and technology materials engineering coating and films
• natural sciences biological sciences biochemistry biomolecules carbohydrates
• engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
• engineering and technology materials engineering ceramics

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

• FP7-PEOPLE-2012-IEF - Marie-Curie Action: "Intra-European fellowships for career development"

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator