Project description DEENESFRITPL Cutting-edge tools for preventing atrial fibrillation, strokes Atrial fibrillation (AF) and stroke are major health care problems in Europe. They are most often the clinical expression of atrial cardiomyopathy, which is under-recognised due to the lack of specific diagnostic tools. Multidisciplinary research and stratified approaches are urgently needed to preempt the AF-related threat to healthy ageing in Europe. EU-funded MAESTRIA is a consortium of clinicians, scientists and pharma industrials who are at the forefront of research and medical care of AF and stroke patients. It will create multi-parametric digital tools based on a new generation of biomarkers that integrate artificial intelligence processing and big data from cutting edge imaging, electrocardiography and omics technologies. It will develop novel diagnostic tools and personalised therapies for AF. Show the project objective Hide the project objective Objective Atrial fibrillation (AF) and stroke are major health care problems in Europe. They are most often the clinical expression of atrial cardiomyopathy, which is under-recognised due to the lack of specific diagnostic tools. Multidisciplinary research and stratified approaches are urgently needed to prevent, diagnose, and treat AF and stroke and preempt the AF-related threat to healthy ageing in Europe. MAESTRIA is a European consortium of 18 clinicians, scientists and Pharma industrials who are at the forefront of research and medical care of AF and stroke patients. It will create multi-parametric digital tools based on a new generation of biomarkers that integrate artificial intelligence (AI) processing and big data from cutting edge imaging, electrocardiography and omics technologies. It will develop novel biomarkers, diagnostic tools and personalized therapies for atrial cardiomyopathy. Digital Twin technologies, a rich data integrator combining biophysics and AI will be used to generate virtual twins of the human atria using patient-specific data. Unique experimental large-animal models, ongoing patient cohorts and a prospective MAESTRIA cohort of patients will provide rigorous validation for new biomarkers and newly developed tools. A dedicated core lab will collect and homogenize clinical data. MAESTRIA will be organized as a user-centered platform, easily accessible via clinical parameters routinely used in European hospitals. A Scientific Advisory Board comprising potential clinician users will help MAESTRIA meet clinical and market needs. Dissemination and visibility of the MAESTRIA consortium mission will benefit from participation of the German Competence Network on Atrial Fibrillation (AFNET), and support from the European Society of Cardiology, clinicians, scientists, and other professional societies. MAESTRIA will be ready to tackle the major challenges of data integration and personalized medicine focused on atrial cardiomyopathy, AF and stroke. Fields of science natural sciencescomputer and information sciencesdata sciencebig datamedical and health scienceshealth sciencespersonalized medicinemedical and health sciencesbasic medicineneurologystrokemedical and health sciencesclinical medicinecardiologynatural sciencescomputer and information sciencesartificial intelligencemachine learning Keywords Atrial cardiomyopathy atrial fibrillation cardiac imaging cardiac electrical signal digital diagnostic platform machine learning artificial intelligence data integration personalised medicine Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.5. - Methods and data Topic(s) SC1-BHC-06-2020 - Digital diagnostics – developing tools for supporting clinical decisions by integrating various diagnostic data Call for proposal H2020-SC1-BHC-2018-2020 See other projects for this call Sub call H2020-SC1-2020-Single-Stage-RTD Funding Scheme RIA - Research and Innovation action Coordinator SORBONNE UNIVERSITE Net EU contribution € 1 657 770,00 Address 21 RUE DE L'ECOLE DE MEDECINE 75006 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 2 848 500,00 Participants (19) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. FONDATION CARDIOMETABOLISME NUTRITION France Net EU contribution € 1 190 730,00 Address BOULEVARD DE L'HOPITAL 47-83 75013 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 190 730,00 ASSISTANCE PUBLIQUE HOPITAUX DE PARIS France Net EU contribution € 660 758,75 Address 55 BOULEVARD DIDEROT 75012 Paris See on map Region Ile-de-France Ile-de-France Val-de-Marne Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 660 758,75 THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD United Kingdom Net EU contribution € 811 862,50 Address WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 811 862,50 THE UNIVERSITY OF BIRMINGHAM United Kingdom Net EU contribution € 435 191,25 Address Edgbaston B15 2TT Birmingham See on map Region West Midlands (England) West Midlands Birmingham Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 435 191,25 KOMPETENZNETZ VORHOFFLIMMERN E.V. Germany Net EU contribution € 2 470 560,00 Address Mendelstrasse 11 48149 Muenster See on map Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 2 476 810,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. ST. VINCENZ-KRANKENHAUS GMBH Germany Net EU contribution € 6 250,00 Address AM BUSDORF 2 33098 Paderborn See on map Region Nordrhein-Westfalen Detmold Paderborn Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 6 250,00 UNIVERSITAETSKLINIKUM ESSEN Germany Net EU contribution € 370 000,00 Address HUFELANDSTRASSE 55 45147 Essen See on map Region Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 370 000,00 UNIVERSITEIT MAASTRICHT Netherlands Net EU contribution € 1 249 837,50 Address MINDERBROEDERSBERG 4 6200 MD Maastricht See on map Region Zuid-Nederland Limburg (NL) Zuid-Limburg Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 249 837,50 ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Greece Net EU contribution € 574 000,00 Address 6 CHRISTOU LADA STR 10561 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 574 000,00 CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) Spain Net EU contribution € 801 000,00 Address CALLE MELCHOR FERNANDEZ ALMAGRO 3 28029 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 801 000,00 THE GENERAL HOSPITAL CORPORATION United States Net EU contribution € 500 000,00 Address FRUIT STREET 55 02114 Boston Ma See on map Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 500 000,00 IMT TRANSFERT France Net EU contribution € 581 250,00 Address 19 PLACE MARGUERITE PEREY 91120 Palaiseau See on map Region Ile-de-France Ile-de-France Essonne Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 581 250,00 CENTRE INTEGRE UNIVERSITAIRE DE SANTE ET DE SERVICES SOCIAUX DE L ESTRIE-CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE Canada Net EU contribution € 0,00 Address 375 RUE ARGYLL J1J 3H5 Sherbrooke See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 605 000,00 SIEMENS HEALTHCARE GMBH Germany Net EU contribution € 726 156,25 Address HENKESTRASSE 127 91052 Erlangen See on map Region Bayern Mittelfranken Erlangen, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 726 156,25 CARISTO DIAGNOSTICS LIMITED United Kingdom Net EU contribution € 531 250,00 Address 234 BOTLEY ROAD NEW BARCLAYS HOUSE OX2 0HP Oxford See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 531 250,00 OWKIN FRANCE France Net EU contribution € 471 875,00 Address 14-16 BOULEVARD POISSONNIERE 75009 PARIS See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Ile-de-France Ile-de-France Paris Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 471 875,00 IDOVEN 1903 SL Spain Net EU contribution € 487 745,00 Address C/PRINCIPE DE VERGARA 128 ESC DR PISO EN 28002 Madrid See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 487 745,00 PREVENTICUS GMBH Germany Net EU contribution € 205 000,00 Address ERNST-ABBE-STRASSE 15 07743 Jena See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Thüringen Thüringen Jena, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 205 000,00 YOURRHYTHMICS Netherlands Net EU contribution € 184 075,00 Address Oxfordlaan 55 6229 EV Maastricht See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Zuid-Nederland Limburg (NL) Zuid-Limburg Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 184 075,00
