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Final Report Summary - MIMOVAX (Alzheimer's disease-treatment targeting truncated Aß40/42 by active immunisation)
Alzheimer's disease (AD) is the most common form of dementia in humans and is caused by the abnormal deposition of Beta-amyloide (BA) plaques associated with extensive neuronal loss in the brain of patients. At present, no effective treatment is available to stop the progressi...
Programme: FP6-LIFESCIHEALTH
Record Number: 52985
Last updated on: 2011-11-03
Final Report Summary - PONT (Disease therapeutic targets, multidisciplinary parallel validation, accelerated drug discovery)
Genomics approaches deliver hundreds of candidate new disease drug targets in a single experiment. However, these targets are poorly characterised, particularly with respect to the medical relevance, and current drug discovery processes are not optimised to handle the huge num...
Programme: FP6-LIFESCIHEALTH
Record Number: 51683
Last updated on: 2011-04-14
Final Report Summary - PEROXISOMES (Integrated project to decipher the biological function of peroxisomes in health and disease)
Peroxisomes are single membrane-bound organelles, present in virtually all eukaryotic cells. In mammals, the size (0.2 - 1 µm), the number and protein content of peroxisomes vary strongly depending on the cell and tissue type as well as on the developmental and physiological s...
Programme: FP6-LIFESCIHEALTH
Record Number: 51814
Last updated on: 2011-04-14
Final Report Summary - SARS/FLU VACCINE (Development of a combined Influenza/SARS vaccine)
In 2002, an atypical pneumonia, characterised by progressive respiratory failure, emerged in southern China. The causative agent was rapidly identified as a new coronavirus - designated as Severe acute respiratory syndrome-associated virus SARS-CoV. The disease swept rapidly t...
Programme: FP6-LIFESCIHEALTH
Record Number: 51823
Last updated on: 2011-04-14
Final Report Summary - IPRAM (Intellectual property rights and assets management course)
The main ambitions of IPRAM was to raise awareness among life scientists and members of technology transfer offices of the commercial potential of their research and the research projects performed within their research institutes, respectively. This is to stimulate technology...
Programme: FP6-LIFESCIHEALTH
Record Number: 47354
Last updated on: 2011-04-14
Final Report Summary - OVCAD (Ovarian Cancer - Diagnosing a Silent Killer)
In Europe 63 000 ovarian cancer cases are diagnosed and 41 000 ovarian cancer patients die annually. 75 % of patients are diagnosed at advanced stages due to an asymptomatic course. 75 % of these patients die within 5 years. Treatment involves surgery followed by chemotherapy....
Programme: FP6-LIFESCIHEALTH
Record Number: 47036
Last updated on: 2011-04-14
Final Report Summary - ENRAH-SME (European Network for research on alternating hemiplegia in childhood for promoting SMEs integration)
ENRAH was a patient driven network. The motivation of the project team was the key to the success and in achieving all project goals under the tight deadlines and with insufficient project budget. The electronic on line format (required to facilitate and secure data collecti...
Programme: FP6-LIFESCIHEALTH
Record Number: 51987
Last updated on: 2011-04-14
Final Report Summary - SMES GO HEALTH (Supporting SME-academia collaboration in the area of biomedical research in FP7 through efficient matching facilities and tailor-made information ...)
SMES GO HEALTH was a European initiative designed to support small and medium-sized enterprises (SMEs) and academic researchers interested in research cooperation and participation in the Seventh Framework Programme (FP7), particularly in the 'Health' area. The objective was t...
Programme: FP6-LIFESCIHEALTH
Record Number: 47348
Last updated on: 2011-04-14
Final Report Summary - CONTICA (Control of Intracellular Calcium in Arrhythmias)
Sudden cardiac death is a major cause of death worldwide. Only a few years ago, it became clear that mutations in the cardiac sarcoplasmic reticulum (SR) Ca2+ release channel, or ryanodine receptor (RyR2), can cause catecholaminergic polymorphic ventricular tachycardia (CPVT),...
Programme: FP6-LIFESCIHEALTH
Record Number: 47051
Last updated on: 2011-04-14
Final Report Summary - X-ALD (X-linked Adrenoleukodystrophy (X-ALD): pathogenesis, animal models and therapy)
X-ALD is the most common (1:18 000) monogenetic disorder affecting the myelin within the Central nervous system (CNS). It affects boys (between 5-12 years), adult males (20-50 years), and women (> 40 years). All forms of X-ALD are characterised by neurological abnormalities, w...
Programme: FP6-LIFESCIHEALTH
Record Number: 51602
Last updated on: 2011-04-14
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