Community Research and Development Information Service - CORDIS

Search projects and results

Results 1 - 10 of 136
Results/page:
12 3 4 5 6 7 8 9 10 > >| 
Final Report Summary - TCAC IN CANCER (Defects in the tricarboxylic acid (KREBS) cycle genes in tumorigenesis)
For the TCAC IN CANCER project, top European cancer research groups working on the association between defects in the Tricarboxylic acid cycle (TCAC) and cancer formed a consortium to: 1) profoundly characterise the human phenotypes to enable identification and efficient can...
Programme: FP6-LIFESCIHEALTH
Record Number: 52000
Last updated on: 2011-04-14
Final Report Summary - LYMPHANGIOGENOMICS (Genome-Wide Discovery and Functional Analysis of Novel Genes in Lymphangiogenesis)
The aim of this project was to discover novel genes important for lymphatic vascular versus blood vascular development and function and to study the functional role and therapeutic potential of their gene products in lymphangiogenesis using state-of-the-art technologies. The l...
Programme: FP6-LIFESCIHEALTH
Record Number: 51639
Last updated on: 2011-04-14
Final Report Summary - TUMOR-HOST GENOMICS (Genome-wide analysis of signaling pathways in regulation of the interactions between tumor and host cells: Applications for cancer therapy)
The ultimate aim of the TUMOR-HOST GENOMICS project was to unravel and validate new targets for anticancer therapy, and new strategies for delivering therapy to tumours. Its specific aims were to: - develop targeted lentiviral libraries for inhibition of selected major cell ...
Programme: FP6-LIFESCIHEALTH
Record Number: 51790
Last updated on: 2011-04-14
Final Report Summary - NCL-MODELS (Dissecting neuronal degeneration: Neuronal ceroid lipofuscinoses from genes to function)
The Neuronal ceroid lipofuscinoses (NCLs) are collectively the most common inherited progressive encephalopathy of childhood. Each form of NCL is characterised by the progressive death of CNS neurons and these rare diseases provide an excellent model to define the molecular ev...
Programme: FP6-LIFESCIHEALTH
Record Number: 51611
Last updated on: 2011-04-14
Final Report Summary - ENOUGH SLEEP (Disorders of sleep regulation: basic mechanisms and thepapeutic perspectives)
The general objectives of the project were the following: 1) To spearhead the first integrated effort at understanding the different mechanisms of sleep regulation using a combined genetic, molecular, electrophysiological and systems approach. 2) To develop novel diagnostic ...
Programme: FP6-LIFESCIHEALTH
Record Number: 51580
Last updated on: 2011-04-14
NOVEL APPROACHES TO PATHOGENESIS, DIAGNOSIS AND TREATMENT OF AUTOIMMUNE DISEASES BASED ON NEW INSIGHTS INTO THYMUS-DEPENDENT SELF-TOLERANCE
ID: 503410
Start date: 2004-01-01, End date: 2008-12-31
Autoimmune diseases are a significant burden for the quality of life and health care cost. Despite intense research efforts, the mechanisms underlying the development of autoimmune diseases are still largely obscure. This obvious ignorance explains why the current treatment of...
Programme: FP6-LIFESCIHEALTH
Record Number: 75307
Last updated on: 2009-08-24
Molecular Imaging for Biologically Optimised Cancer Therapy
ID: 505785
Start date: 2004-03-01, End date: 2008-12-31
Early tumour detection and response monitoring require maximum sensitivity and specificity of the imaging methods. The programme focuses on the clinical evaluation and development of new more specific molecular tracers for the early detection of tumour cells. A large number of...
Programme: FP6-LIFESCIHEALTH
Record Number: 75338
Last updated on: 2008-10-30
Baculovirus vectors for gene therapy
[PROJECT] BACULOGENES - Baculovirus vectors for gene therapy
ID: 37541
Start date: 2007-01-01, End date: 2010-03-31
Baculovirus (BV) Autographa californica multicapsid nuclear polyhedrosis virus is a promising new vector for gene therapy: it is inherently safe and can deliver large pieces of DNA to mammalian cells; its own genes are not transcripted in mammalian cells, and it is not known t...
Programme: FP6-LIFESCIHEALTH
Record Number: 84998
Last updated on: 2010-10-20
Autoimmune polyendocrine syndrome type I - a rare disorder of childhood as a model for autoimmunity
ID: 5223
Start date: 2005-05-01, End date: 2008-04-30
Autoimmune polyendocrine syndrome type I (APS I), a rare genetic disorder of childhood, has proven to be an invaluable tool in understanding autoimmune reactions. APS I (OMIM 240300), also known as APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy), is a s...
Programme: FP6-LIFESCIHEALTH
Record Number: 75913
Last updated on: 2009-12-14
Hepatic and adipose tissue and functions in the metabolic syndrome
ID: 18734
Start date: 2005-11-01, End date: 2010-10-31
The Metabolic Syndrome is a major risk marker for type 2 diabetes and for cardiovascular disease. Recent evidence suggests a crucial role for fat accumulation in the liver in the development of the Metabolic Syndrome. The hypothesis of the HEPADIP project is that this reflects...
Programme: FP6-LIFESCIHEALTH
Record Number: 78435
Last updated on: 2012-11-20
12 3 4 5 6 7 8 9 10 > >| 
List retrieved on: 2017-10-23
Follow us on: RSS Facebook Twitter YouTube Managed by the EU Publications Office Top