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From Immune Responses in Rare Autoimmune Diseases to novel Therapeutic Intervention Strategies-a personalized Medicine approach
ID: 5264
Start date: 2004-11-01, End date: 2007-10-31
The European research network, AUTOROME, represents Centers of Excellence in Europe where recent technologies in studying the pathophysiology of humoral and cellular autoimmunity are combined and applied to improve in a personalized manner diagnosis and treatment of rare human...
Record Number: 75915
Last updated on: 2008-07-21
Development of early non-invasive biomarkers and means for the diagnosis and progression monitoring of pre-eclampsia and tailoring putative therapies
ID: 37244
Start date: 2006-12-01, End date: 2009-11-30
Preeclampsia (PET), de-novo hypertension & proteinuria after mid gestation, affects 5-7% of all pregnancies. Cases may develop life threatening haemolysis-elevated liver enzymes-low platelets (HELLP) or renal failure, cerebral haemorrhages & eclampsia, IUGR, placental abruptio...
Record Number: 84948
Last updated on: 2010-03-02
Genetic and environmental determinants of melanoma: translation into behavioural change
ID: 18702
Start date: 2005-12-01, End date: 2011-05-31
GenoMEL, formerly known as the Melanoma Genetics Consortium, has focused on the identification of familial high penetrance melanoma genes. The joint programme of research has been very successful in the identification of susceptibility genes and developing joint data collectio...
Record Number: 84807
Last updated on: 2011-07-26
ENFIN - an experimental network for functional integration
ID: 518254
Start date: 2005-11-15, End date: 2011-05-14
We propose to form a Network of Excellence in the area of bioinformatics to provide a Europe-wide integration of computational approaches in systems biology. This network will be focused on the development and critical assessment of computational approaches in this area, but u...
Record Number: 75903
Last updated on: 2013-03-26
Reprogramming the immune System for the Establishment of Tolerance
ID: 512090
Start date: 2005-03-01, End date: 2010-08-31
Transplantation dramatically improves the survival of patients with end-stage failure of vital organs. However, as a directconsequence of the immunosuppressive drugs permanently required to prevent rejection, recipients have a significantly increased risk of infection and mali...
Record Number: 75691
Last updated on: 2010-10-12
Innovative chemokine-based therapeutic strategies for autoimmunity and chronic inflammation
ID: 518167
Start date: 2005-11-01, End date: 2010-10-31
The general objective of INNOCHEM is to develop innovative chemokine-based therapeutic strategies for autoimmunity and chronic inflammation. The project is based on the scientific excellence of the applicants, which have made major recognized contributions to the field since t...
Record Number: 85793
Last updated on: 2011-03-02
ID: 5216
Start date: 2005-06-01, End date: 2010-07-31
The knowledge generated by the sequencing of the human genome will enable the development of more effective strategies for preventing, diagnosing and treating human diseases, and consequently decrease morbidity and mortality. One can therefore anticipate that children should b...
Record Number: 75912
Last updated on: 2013-03-26
Biosensors based on membrane organisation to replace animal testing
ID: 5199
Start date: 2005-01-01, End date: 2007-06-30
The ultimate goal is the development and validation of alternative techniques to replace animal testing in procedures concerning drug screening and environmental control. The first step is the organisation of a Specific Support Action that brings together fragmented industrial...
Record Number: 81216
Last updated on: 2013-03-26
Genetics of Sepsis in Europe
[PROJECT] GENOSEPT - Genetics of Sepsis in Europe
ID: 512155
Start date: 2005-01-01, End date: 2008-12-31
GenOSept is a specific targeted research project (STREP) which uses a multidisciplinary fundamental genomics approach (gene expression, structural genomics, population genetics) to examine genetic predisposition to sepsis. Sepsis (life-threatening infection) is a major public ...
Record Number: 75702
Last updated on: 2013-03-26
Dedicated integration and modelling of novel data and prior knowledge to enable systems biology
ID: 512143
Start date: 2005-01-01, End date: 2008-06-30
We will demonstrate the power of a Systems Biology approach to study the regulatory network structure of the most fundamental biological process in eukaryotes: the cell cycle. An integrative approach will be applied to build a basic model of the cell cycle, in four different s...
Record Number: 74100
Last updated on: 2013-03-26
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List retrieved on: 2017-05-27
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