Community Research and Development Information Service - CORDIS

Search projects and results

Results 1 - 10 of 535
Results/page:
12 3 4 5 6 7 8 9 10 > >| 
Development of early non-invasive biomarkers and means for the diagnosis and progression monitoring of pre-eclampsia and tailoring putative therapies
ID: 37244
Start date: 2006-12-01, End date: 2009-11-30
Preeclampsia (PET), de-novo hypertension & proteinuria after mid gestation, affects 5-7% of all pregnancies. Cases may develop life threatening haemolysis-elevated liver enzymes-low platelets (HELLP) or renal failure, cerebral haemorrhages & eclampsia, IUGR, placental abruptio...
Programme: FP6-LIFESCIHEALTH
Record Number: 84948
Last updated on: 2010-03-02
Placental Growth Factor (PlGF): new diagnostic and therapeutic applications in cardiovascular disease
ID: 37254
Start date: 2007-01-01, End date: 2009-03-31
The proposed Strep evaluates the potential of PlGF as a pharmaceutical for major chronic progressive cardiac disorders (ischemic heart disease, heart failure and arterial insufficiency (intermittent claudication and critical limb ischemia)) and as a biomarker for cardiovascula...
Programme: FP6-LIFESCIHEALTH
Record Number: 84951
Last updated on: 2013-03-26
Integrated genomics, clinical research and care in hypertension
ID: 37093
Start date: 2006-11-01, End date: 2011-01-31
The InGenious HyperCare Network of Excellence's goal is that of integrating complementary but still fragmented experience in the mechanisms of blood pressure control and hypertension development, in phenotyping initiation and progression of organ damage and exploring genetics,...
Programme: FP6-LIFESCIHEALTH
Record Number: 84934
Last updated on: 2013-03-26
Final Report Summary - INGENIOUS HYPERCARE (Integrated Genomics, Clinical Research and Care in Hypertension)
A better prevention of hypertension and hypertension-related cardiovascular events is an essential public health goal in Europe, where cardiovascular diseases are the major cause of mortality and morbidity. Despite the widely shared opinion that hypertension has an important h...
Programme: FP6-LIFESCIHEALTH
Record Number: 53036
Last updated on: 2012-05-24
Identification of genetic roots of coronary artery disease by combining stepwise genome wide association studies with transcriptomic and functional genomic investigation of relevant genetic variants
ID: 37593
Start date: 2006-10-01, End date: 2011-03-31
The heritability of coronary artery disease (CAD) and myocardial infarction (MI) has been unequivocally demonstrated. However, traditional technology, for example based on investigation of candidate genes, or linkage analysis, has failed to elucidate the genetic roots of the N...
Programme: FP6-LIFESCIHEALTH
Record Number: 85010
Last updated on: 2013-03-26
Development of New Drugs for the Treatment of Malaria
ID: 18834
Start date: 2005-12-01, End date: 2011-05-31
Leading groups of malaria researchers will integrate their expertise in malaria biology and drug development to exploit new scientific and political opportunities to secure the development of a portfolio of viable novel AntiMalarial drugs. New chemical entities will be commerc...
Programme: FP6-LIFESCIHEALTH
Record Number: 78405
Last updated on: 2011-12-20
Genetic and environmental determinants of melanoma: translation into behavioural change
ID: 18702
Start date: 2005-12-01, End date: 2011-05-31
GenoMEL, formerly known as the Melanoma Genetics Consortium, has focused on the identification of familial high penetrance melanoma genes. The joint programme of research has been very successful in the identification of susceptibility genes and developing joint data collectio...
Programme: FP6-LIFESCIHEALTH
Record Number: 84807
Last updated on: 2011-07-26
Epigenetic treatment of neoplastic disease
ID: 518417
Start date: 2005-11-01, End date: 2011-04-30
Chromatin is epigenetically modified to regulate gene expression. Upstream signals induce complex patterns of enzyme-catalyzed modifications of DNA and histones, key protein components of chromatin. These epigenetic modifications create docking sites for other regulators and f...
Programme: FP6-LIFESCIHEALTH
Record Number: 78780
Last updated on: 2011-05-30
Identification of early disease markers, novel pharmacologically tractable targets and small molecule phenotypic modulators in Huntington's Disease'
ID: 37472
Start date: 2007-01-01, End date: 2010-12-31
Huntington's is a devastating neurodegenerative disease with many unmet patient needs. There are no known ways of slowing or preventing the neuro-degeneration, and clinical trials in man are hampered by the slow disease progression and the absence of suitable biomarkers of sho...
Programme: FP6-IST
Record Number: 96397
Last updated on: 2011-01-24
Final Report Summary - TAMAHUD (Identification of early disease markers, novel pharmacologically tractable targets and small molecule phenotypic modulators in Huntington's Disease)
There are no known ways of slowing or preventing the neurodegeneration, and clinical trials in man are hampered by the slow disease progression and the absence of suitable biomarkers of short-term progression. The genetics of HD is characterised by, and involves the expansion ...
Programme: FP6-IST
Record Number: 52931
Last updated on: 2011-11-03
12 3 4 5 6 7 8 9 10 > >| 
List retrieved on: 2017-02-22