Results 11 - 20 of 2310
[RESULT IN BRIEF] Comprendre les effets des radiations
Chez l'homme, le risque cancérigène induit par exposition aux rayonnements ionisants n'est pas toujours facile à évaluer.
Programme: FP5-EAECTP C
Record Number: 84652
Last updated on: 2008-12-15
[REPORT SUMMARY] Telomeres modulate radiation response in vitro and in vivo - Vegetable intake prevents excessive telomere shortening
Mouse studies in the frame of this and previous EU project have determined that telomere length modulates radiosensitivity. Thus, telomerase KO mice with short telomeres (late generation) are more sensitive that telomere KO mice with long telomeres (earlier generation KO mice)...
Programme: FP5-EAECTP C
Record Number: 44384
Last updated on: 2007-08-22
[REPORT SUMMARY] Genomic instability and telomere length, radiation sensitivity of human mammary epithelial cells in culture
Human mammary epithelial cells derived from normal breast tissue from three women subjected to spontaneous reduction were analysed. These cells may spontaneously overcome the normal proliferation limits by loosing expression of p16 protein. The karyotype evolution of HMECs was...
Programme: FP5-EAECTP C
Record Number: 44381
Last updated on: 2007-08-22
[REPORT SUMMARY] Telomeres and telomerase in radio-sensitivity and gene amplification
Telomeres and telomerase play key roles in the maintenance of genome stability. Chiara Mondello, in collaboration with Elena Giulotto, has shown that in telomerase expressing cells, very short telomeres do not increase cellular and chromosomal radiosensitivity, as they do in t...
Programme: FP5-EAECTP C
Record Number: 44380
Last updated on: 2007-08-22
[RESULT IN BRIEF] La importancia de que los telómeros sean largos
El proyecto europeo TELOSENS se centró en continuar la línea de investigación que pretende determinar el papel de los telómeros en la predisposición a los daños causados por la radiación y a la sensibilidad a los agentes genotóxicos.
Programme: FP5-EAECTP C
Record Number: 84636
Last updated on: 2008-12-08
List retrieved on: 2017-08-02