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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 2299
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Phase I/II ex vivo gene therapy clinical trial for recessive dystrophic epidermolysis bullosa using skin equivalent grafts genetically corrected with a COL7A1-encoding SIN retroviral vector
ID: 261392
Start date: 2011-03-01, End date: 2017-12-31
RDEB is one of the most severe rare genetic skin diseases of children and adults characterized by skin blistering resulting from lack of expression of type VII collagen. There is no treatment for this life-threatening disease. In March 2009, we obtained the orphan drug design...
Programme: FP7-HEALTH
Record Number: 98248
Last updated on: 2017-05-26
Periodic Report Summary 4 - GENEGRAFT (Phase I/II ex vivo gene therapy clinical trial for recessive dystrophic epidermolysis bullosa using skin equivalent grafts genetically corrected with a COL7A1-encoding SIN retroviral vector)
Project Context and Objectives: PROJECT CONTEXT Recessive Dystrophic Epidermolysis Bullosa (RDEB) is one of the most severe inherited skin disorders affecting children and adults. RDEB is caused by loss-of-function recessive mutations in COL7A1 encoding type VII collagen, the...
Programme: FP7-HEALTH
Record Number: 202516
Last updated on: 2017-08-16
Adding Another Dimension – Arrays of 3D Bio-Responsive Materials
ID: 340469
Start date: 2014-11-01, End date: 2019-10-31
This proposal is focused in the areas of chemical medicine and chemical biology with the key drivers being the discovery and development of new materials that have practical functionality and application. The project will enable the fabrication of thousands of three-dimension...
Programme: FP7-IDEAS-ERC
Record Number: 192351
Last updated on: 2016-11-28
Periodic Report Summary 2 - ADREEM (Adding Another Dimension – Arrays of 3D Bio-Responsive Materials)
The ADREEM team has been developing new chemistries and new materials that have biological and biomedical applications. For example imagine: • A polymer (we call them “smartpolymers”) that has a drug attached to it, but which only allows the drug to be released when...
Programme: FP7-IDEAS-ERC
Record Number: 202282
Last updated on: 2017-08-14
Ion homeostasis and volume regulation of cells and organelles
ID: 294435
Start date: 2012-04-01, End date: 2017-03-31
"The regulation of ion concentrations in the cytoplasm and in the lumen of intracellular vesicles provides suitable environments for biochemical reactions, gradients for signal transduction, and generates osmotic gradients for the regulation of the volume of cells and intrace...
Programme: FP7-IDEAS-ERC
Record Number: 102290
Last updated on: 2015-03-10
Final Report Summary - CYTOVOLION (Ion homeostasis and volume regulation of cells and organelles)
When cells are exposed to external solutions that contain less salt, they will swell – a dangerous situation as the cells may even burst and die at some point. Therefore, they must have mechanisms to reduce their volume, a process called regulatory volume decrease. Cell...
Programme: FP7-IDEAS-ERC
Record Number: 202741
Last updated on: 2017-08-14
Gentherapie bei Netzhauterkrankungen
Die Netzhaut ist ein Sinnesorgan des Zentralnervensystems zur Wahrnehmung visueller Reize. Neue therapeutische Ansätze zur Behandlung degenerativer Netzhauterkrankungen, bei denen defekte Gene in der Netzhaut ersetzt werden (funktioneller Gentransfer), könnten Millionen von Me...
Programme: FP7-HEALTH
Record Number: 85821
Last updated on: 2013-02-18
Available languages: DE, EN, ES, FR, IT, PL
Terapia génica para las enfermedades de la retina
La retina es el receptor sensorial de la vista del sistema nervioso central. Se han propuesto nuevos enfoques para el tratamiento de las enfermedades degenerativas de la retina basados en la transferencia del gen funcional que podrían beneficiar a millones de afectados en todo...
Programme: FP7-HEALTH
Record Number: 85821
Last updated on: 2013-02-18
Available languages: DE, EN, ES, FR, IT, PL
Gene therapy for retinal disorders
The retina represents the visual sensory receptor of the central nervous system. Novel treatment approaches for retinal degeneration disorders based on the transfer of the functional gene could benefit millions of sufferers worldwide.
Programme: FP7-HEALTH
Record Number: 85821
Last updated on: 2013-02-18
Available languages: DE, EN, ES, FR, IT, PL
La thérapie génique au service des maladies de la rétine
La rétine constitue le récepteur visuel du système nerveux central. De nouvelles approches thérapeutiques pour les maladies dégénératives de la rétine fondées sur le transfert du gène fonctionnel pourraient profiter à des millions de personnes dans le monde.
Programme: FP7-HEALTH
Record Number: 85821
Last updated on: 2013-02-18
Available languages: DE, EN, ES, FR, IT, PL
12 3 4 5 6 7 8 9 10 > >| 
List retrieved on: 2017-08-20
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