Results 1 - 10 of 51
ID: IC18960056
Start date: 1996-10-01, End date: 2000-07-31
The main objective of the project is the development of new antimalarial drugs that interact with the malarial parasite phospholipid metabolism and could provide a solution to P. falciparum polychemoresistant malaria.
Although there is no indication of potential resistance to...
Programme: FP4-INCO
Record Number: 37549
Last updated on: 2001-12-07
[PROJECT] CHIBCHA - Genetic study of Common Hereditary Bowel Cancers in Hispania and the Americas
ID: 223678
Start date: 2009-06-01, End date: 2013-05-31
Colorectal cancer (CRC) is common in both sexes, has relatively poor outcome and has no major avoidable risk factor. Recent studies have shown that common inherited single nucleotide polymorphisms (SNPs) can increase cancer risk. We have shown CRC risk to be associated with S...
Programme: FP7-HEALTH
Record Number: 91245
Last updated on: 2017-06-05
[PROJECT] EMLI - Phase-i and ii trials of the malaria pre-erythrocytic vaccine lsa-3 and refinement of measurable outcomes (EMLI)
ID: QLK2-CT-2001-01886
Start date: 2002-01-01, End date: 2006-06-30
This proposal is based on a decade of European-sponsored research, which led to the rational identification, characterization, and demonstration of protection in Chimpanzees by LSA3. It aims at testing, in phase-I and conditional phase-II trials, the protective effect demonstr...
Programme: FP5-LIFE QUALITY
Record Number: 60259
Last updated on: 2005-04-12
ID: IC18980387
Start date: 1999-02-01, End date: 2001-02-28
Programme: FP4-INCO
Record Number: 47342
Last updated on: 1999-04-20
[PROJECT] NOVEL ANTIMALARIALS - Malarial chemotherapy targeting plasmodial phospholipid biosynthesis: implementation of a prodrug strategy for orally active compounds
ID: QLK2-CT-2000-01166
Start date: 2001-01-01, End date: 2005-06-30
We will develop a new class of ant malarial drug that target membrane biogenesis of the erythrocyte stage of Plasmodium falciparum. We have established thatphospholipid synthesis of the parasite, but not the host, is specifically blocked, and that multiresistant malaria is sus...
Programme: FP5-LIFE QUALITY
Record Number: 58509
Last updated on: 2005-04-12
ID: IC18980338
Start date: 1998-09-01, End date: 2002-11-30
Programme: FP4-INCO
Record Number: 46468
Last updated on: 1999-03-11
[PROJECT] E PIAF - Enhanced Protective Immunity Against Filariasis
ID: 242131
Start date: 2010-03-01, End date: 2014-08-31
Filarial infections remain a major public health problem in West and Central Africa. Three filarial species are involved: Onchocerca volvulus (onchocerciasis or river blindness); Wuchereria bancrofti (lymphatic filariasis); and Loa loa (the eye worm). Treatment of onchocercia...
Programme: FP7-HEALTH
Record Number: 94066
Last updated on: 2017-05-25
[PROJECT] AFRICA BUILD - AFRICA BUILD (Building a Research and Education Infrastructure for Africa)
ID: 266474
Start date: 2011-08-01, End date: 2014-07-31
Topic: AFRICA BUILD aims to improve capacity for health research and education in Africa, through Information Technologies (IT). It will provide innovative learning and research opportunities. Background: The EU has supported many IT and health initiatives, with significant r...
Programme: FP7-HEALTH
Record Number: 99621
Last updated on: 2017-05-26
[PROJECT] MALCROSS - Genetic analysis of the chloroquine drug resistance and accelerated-resistance-to-multiple-drugs phenotype in the human malarial parasite plasmodium falciparum
ID: QLK2-CT-2002-00774
Start date: 2002-11-01, End date: 2006-01-31
Hopes of radical malaria control have been thwarted by the emergence and rapid spread of human malarial parasites that are resistant to every common drug available, including chloroquine, quinine, mefloquine, pyrimethamine, cycloguanil and sulfadoxin. To make matters worse, su...
Programme: FP5-LIFE QUALITY
Record Number: 69974
Last updated on: 2005-12-09
ID: IC18960071
Start date: 1996-12-01, End date: 1999-12-31
* to identify P. falciparum centromere sequences
* to analyze spatial and temporal chromatin changes and their effect on transcriptional activity in P. falciparum
* to develop an in vitro plasmodial telomerase assay
* to identify and clone the P. falciparum telomerase includin...
Programme: FP4-INCO
Record Number: 35368
Last updated on: 2001-12-07
List retrieved on: 2017-08-02
