Results 1 - 10 of 1848
The main goal of MITIN was to elucidate the interplay between the insulin signaling pathway and the mitochondrial function through the combination of computational tools and molecular omics technologies in a multidisciplinary, integrated system biological approach. MITIN...
Programme: FP7-HEALTH
Record Number: 196523
Last updated on: 2017-03-27
[PROJECT] MITIN - INTEGRATION OF THE SYSTEM MODELS OF INSULIN SIGNALLING AND OF MITOCHONDRIAL FUNCTION AND ITS APPLICATION IN THE STUDY OF COMPLEX DISEASES
ID: 223450
Start date: 2008-11-01, End date: 2011-10-31
A common trait to disorders such as type 2 diabetes or obesity is the development of insulin resistance. There is evidence indicating the existence of a bidirectional cross-talk between insulin signalling and mitochondrial function that may be relevant for the pathogenesis of...
Programme: FP7-HEALTH
Record Number: 88487
Last updated on: 2017-05-29
The main goal of MITIN is to elucidate the interplay between the insulin signalling pathway and the mitochondrial function through the combination of computational tools and molecular omics technologies in a multidisciplinary, integrated system biological approach.
The specif...
Programme: FP7-HEALTH
Record Number: 45400
Last updated on: 2011-03-29
Project context and objectives:
The main goal of MITIN was to elucidate the interplay between the insulin signalling pathway and the mitochondrial function through the combination of computational tools and molecular omics technologies in a multidisciplinary, integrated sys...
Programme: FP7-HEALTH
Record Number: 53632
Last updated on: 2012-07-23
[PROJECT] EUROCANPLATFORM - A European Platform for Translational Cancer Research
ID: 260791
Start date: 2011-01-01, End date: 2016-12-31
Europe has a number of advantages as regards developing translational cancer research, yet there is no clear European strategy to meet the increasing burden posed by cancer. The FP6 Eurocan+Plus project analysed the barriers underlying the increasing fragmentation of cancer r...
Programme: FP7-HEALTH
Record Number: 97701
Last updated on: 2017-05-29
[PROJECT] RATHER - Rational Therapy for Breast Cancer: Individualized Treatment for Difficult-to-Treat Breast Cancer Subtypes
ID: 258967
Start date: 2011-01-01, End date: 2018-06-30
Cancer genotyping has identified a number of correlations between mutations in specific genes and responses to targeted anti-cancer drugs, with many mutations occurring in kinases or downstream signaling components. While there are several ongoing large-scale genome re-sequen...
Programme: FP7-HEALTH
Record Number: 97660
Last updated on: 2017-07-16
[PROJECT] Danger ATP - Regulation of inflammatory response by extracellular ATP and P2X7 receptor signalling: through and beyond the inflammasome
ID: 614578
Start date: 2014-09-01, End date: 2019-08-31
Inflammatory diseases affect over 80 million people worldwide and accompany many diseases of industrialized countries, being the majority of them infection-free conditions. There are few efficient anti-inflammatory drugs to treat chronic inflammation and thus, there is an urg...
Programme: FP7-IDEAS-ERC
Record Number: 192054
Last updated on: 2016-03-31
Adenosine triphosphate (ATP) is the molecule in charge to transport the chemical energy of the cell and maintain cellular metabolism. When a tissue is damaged, its cells release their intracellular content, and when ATP reaches high extracellular concentration, it signals to...
Programme: FP7-IDEAS-ERC
Record Number: 201432
Last updated on: 2017-07-24
[REPORT SUMMARY] Radio-sensitivity, DNA repair and biology of telomeres in radiosensitive individuals
Fanconi anemia (FA) patients show accelerated telomere shortening. In order to get further insights in to the role of the FA pathway in telomere biology, Jordi Surralles and his team studied whether FANCD2, a key downstream factor in this pathway, binds to telomeres. They inve...
Programme: FP5-EAECTP C
Record Number: 44382
Last updated on: 2007-08-22
[REPORT SUMMARY] Telomere and whole genome tri-dimensional reconstruction of inter-phase nuclei architecture in response to ionising radiation
Jordi Surralles' objective was to study the architecture of the inter-phase nuclei from the telomere perspective and it response to ionising radiation. He found that telomeres have a defined 3D distribution pattern inside the interphase nucleus that is independent of histone H...
Programme: FP5-EAECTP C
Record Number: 44383
Last updated on: 2007-08-22
List retrieved on: 2017-08-02
