Results 51 - 60 of 19448
[REPORT SUMMARY] Periodic Report Summary 2 - RELATIVISM (The Emergence of Relativism -- Historical, Philosophical and Sociological Perspectives)
Summary of the major achievements since the start of the project To begin with some numbers, since its start 2,5 years ago, members of the project have written about 30 papers or book chapters (of which mor than a dozen have already appeared in print); they have participated...
Programme: FP7-IDEAS-ERC
Record Number: 201415
Last updated on: 2017-07-24
[PROJECT] RELATIVISM - "The Emergence of Relativism -- Historical, Philosophical and Sociological Perspectives"
ID: 339382
Start date: 2014-06-01, End date: 2019-05-31
"Although philosophers as well as scientists are frequently involved in debates over the threat or promise of relativism, there has been little detailed historical, philosophical or sociological work on its emergence and early development. This project addresses this lacuna i...
Programme: FP7-IDEAS-ERC
Record Number: 185405
Last updated on: 2015-03-11
[PROJECT] CHD-IPS - Modeling congenital heart disease (CHD) in ISL1+ cardiovascular progenitors from patient-specific iPS cells
ID: 261053
Start date: 2011-03-01, End date: 2017-02-28
Tetralogy of Fallot (TOF) is the most common congenital heart disease (CHD) occurring 1 in 3000 births. Genetic studies have identified numerous genes that are responsible for inherited and sporadic forms of TOF, most of which encode key molecules that are part of regulatory ...
Programme: FP7-IDEAS-ERC
Record Number: 98145
Last updated on: 2017-05-26
[REPORT SUMMARY] Final Report Summary - CHD-IPS (Modeling congenital heart disease (CHD) in ISL1+ cardiovascular progenitors from patient-specific iPS cells)
Congenital heart disease (CHD) is the most common human birth defect and causes a huge burden on patients, their families and health care professionals as well as our society as a whole. However, the molecular basis of the complex malformation of the heart is only poorly...
Programme: FP7-IDEAS-ERC
Record Number: 201917
Last updated on: 2017-07-24
[REPORT SUMMARY] Final Report Summary - VIRAFRONT (Viral frontiers – species barriers of hepatitis C virus replication)
The major objective of VIRAFRONT was to define the determinants that preclude propagation of hepatitis C virus (HCV), a virus with narrow species tropism that only infects humans and chimpanzees, in mouse liver cells. We have created novel mouse liver-derived cell lines to...
Programme: FP7-IDEAS-ERC
Record Number: 201901
Last updated on: 2017-07-24
[PROJECT] VIRAFRONT - Viral frontiers – species barriers of hepatitis C virus replication
ID: 281473
Start date: 2012-02-01, End date: 2017-01-31
"RNA viruses are responsible for important acute, chronic as well as emerging human infections. While some of these viruses – like for instance the hepatitis C virus (HCV) – are highly species-specific, others (e.g. Dengue Virus) infect different host species. These latter vi...
Programme: FP7-IDEAS-ERC
Record Number: 102346
Last updated on: 2015-08-03
[PROJECT] ParaMotSig - Receptor signalling mediating malaria parasite motility
ID: 281719
Start date: 2012-04-01, End date: 2017-03-31
Plasmodium sporozoites are the motile forms of the malaria parasite injected into the host by a mosquito. Sporozoite motility is essential for tissue penetration as well as host cell invasion and thus pathogenesis suggesting that blocking motility could potentially add a new ...
Programme: FP7-IDEAS-ERC
Record Number: 101482
Last updated on: 2016-03-18
[REPORT SUMMARY] Final Report Summary - PARAMOTSIG (Receptor signalling mediating malaria parasite motility)
Plasmodium sporozoites are the motile forms of the malaria parasite injected into the vertebrate host by a mosquito. Sporozoites are ‘born’ in parasitic oocysts at the mosquito gut from where they need to exit to enter salivary glands. Within these glands they can reside...
Programme: FP7-IDEAS-ERC
Record Number: 201897
Last updated on: 2017-07-24
[REPORT SUMMARY] Final Report Summary - RC3H1/2-SPECIFICITY (Specificity of Rc3h1/2 proteins in post-transcriptional control of immunity and autoimmune disease)
Our research in the grant 218666_Rc3h1/2-specificity was successful as it showed that the Roquin-1 and Roquin-2 encoding Rc3h1 and Rc3h2 genes serve redundant functions in T cells, but nevertheless each one of them is essential for the survival of mice. These findings provided...
Programme: FP7-IDEAS-ERC
Record Number: 201893
Last updated on: 2017-07-24
[PROJECT] RC3H1/2-SPECIFICITY - Specificity of Rc3h1/2 proteins in post-transcriptional control of immunity and autoimmune disease
ID: 281666
Start date: 2011-11-01, End date: 2016-10-31
We are constantly protected by our adaptive immune system. Its functioning requires precise control of gene expression in lymphocytes, since deregulation can cause autoimmune diseases (affecting ~5% of our population) as well as allergic reactions (~9-16%, with increasing inc...
Programme: FP7-IDEAS-ERC
Record Number: 100840
Last updated on: 2016-10-31
List retrieved on: 2017-08-02
