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Final Report Summary - MAIN (Targeting cell migration in chronmic inflammation)
Chronic inflammation is a prototypic systemic disorder resulting from the dysregulation of multiple, mechanistically unrelated higher order biological processes. In chronic inflammatory diseases a variety of 'inputs' effect the recruitment and activation of immune and inflamma...
Programme: FP6-LIFESCIHEALTH
Record Number: 51597
Last updated on: 2012-10-03
Final Report Summary - INGENIOUS HYPERCARE (Integrated Genomics, Clinical Research and Care in Hypertension)
A better prevention of hypertension and hypertension-related cardiovascular events is an essential public health goal in Europe, where cardiovascular diseases are the major cause of mortality and morbidity. Despite the widely shared opinion that hypertension has an important h...
Programme: FP6-LIFESCIHEALTH
Record Number: 53036
Last updated on: 2012-05-24
Final Report Summary - CARDIOGENICS (Identification of genetic roots of coronary artery disease by combining stepwise genome wide association studies with genomic investigation …)
The heart is the organ that works non-stop to keep the blood circulation going. Its own oxygen needs are supplied by blood vessels that form a crown at the 'top' of the heart, hence the name Coronary artery disease (CAD) for constrictions in these arteries. Most often, these c...
Programme: FP6-LIFESCIHEALTH
Record Number: 53035
Last updated on: 2012-05-24
Final Report Summary - FGENTCARD (Functional genomic diagnostic tools for coronary artery disease)
Progress in functional genomics technologies have dramatically increased the density of gene expression datasets providing information on the expression of individual genes and gene networks at the levels of transcription, translation, protein abundance and activity, and metab...
Programme: FP6-LIFESCIHEALTH
Record Number: 52956
Last updated on: 2011-12-14
Final Report Summary - EPITRON (Epigenetic treatment of neoplastic disease)
The ultimate aim of the EPITRON project was to define and validate the concept of epigenetic treatment of cancer. In order to achieve it the project consortium focused on: - providing a molecular understanding of the genome-wide genetic and epigenetic consequences of the for...
Programme: FP6-LIFESCIHEALTH
Record Number: 52998
Last updated on: 2011-11-25
Final Report Summary - GENOMEL (Genetic and environmental determinants of melanoma: translation into behavioural change)
The ultimate aim of the GENOMEL project was to investigate the genetic and environmental risk factors for melanoma. For this purpose it sought to develop and support collaborations between member groups to: - identify melanoma susceptibility genes; - assess the risk of mel...
Programme: FP6-LIFESCIHEALTH
Record Number: 53000
Last updated on: 2011-11-25
Final Report Summary - EURATOOLS (European rat tools for functional genomics)
The EURATOOLS project aimed to: 1. develop reagents and tools for high throughput analysis of the rat genome that would accelerate progress in rat genetics; 2. create a research environment conducive to rapid identification of genes and pathways underlying complex rat dise...
Programme: FP6-LIFESCIHEALTH
Record Number: 52976
Last updated on: 2011-11-03
Final Report Summary - RISET (Reprogramming the immune System for the Establishment of Tolerance)
Transplantation dramatically improves the survival of patients with established organ failure. The transplant is literally a life saver and the short-term prospects of most transplant patients are very good. However, in the longer term many of these patients face serious healt...
Programme: FP6-LIFESCIHEALTH
Record Number: 52919
Last updated on: 2011-11-03
Final Report Summary - ENDOTRACK (Tracking the endocytic routes of growth factor receptor complexes and their modulatory role on signalling)
The ENDOTRACK project aimed at gaining conceptual advance into the signalling function of Growth factors (GFs) from an unconventional perspective, namely by exploring the role of endocytic trafficking in the modulation of GF signalling. It further aimed at translating the gene...
Programme: FP6-LIFESCIHEALTH
Record Number: 47074
Last updated on: 2011-11-03
Final Report Summary - MIMOVAX (Alzheimer's disease-treatment targeting truncated Aß40/42 by active immunisation)
Alzheimer's disease (AD) is the most common form of dementia in humans and is caused by the abnormal deposition of Beta-amyloide (BA) plaques associated with extensive neuronal loss in the brain of patients. At present, no effective treatment is available to stop the progressi...
Programme: FP6-LIFESCIHEALTH
Record Number: 52985
Last updated on: 2011-11-03
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List retrieved on: 2017-11-20
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