Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 2014
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Final Report Summary - ABATSYNAPSE (Evolution of Alzheimer’s Disease: From dynamics of single synapses to memory loss)
During recent years, the preclinical stage of Alzheimer's disease (AD) has become a major focus of research. Continued failures in clinical trials and the realization that early intervention may offer better therapeutic outcome triggered a conceptual shift from the late-stage...
Programme: FP7-IDEAS-ERC
Record Number: 214044
Last updated on: 2018-01-15
Final Report Summary - DCSUBSET (Cross-species characterisation of CD8alpha+ dendritic cells and their role in immune regulation)
Classical dendritic cells (cDCs) are leucocytes that play a key role in innate immunity as well as the initiation and regulation of T cell responses. cDCpoiesis starts with commitment of a bone marrow (BM) haematopoietic progenitor, known as the classical DC precursor (CDP)...
Programme: FP7-IDEAS-ERC
Record Number: 214045
Last updated on: 2018-01-15
Final Report Summary - GENOVAR (Sequence based strategies to identify genetic variation associated with mental retardation and schizophrenia)
The goal of this project was to use sequence based strategies to identify genetics factors involved disorders of the brain, specifically schizophrenia and intellectual disability. Within the project, both sporadic cases of the disorder (healthy parents, affected offspring) and...
Programme: FP7-IDEAS-ERC
Record Number: 214052
Last updated on: 2018-01-15
Final Report Summary - RNAI (Unveiling the Molecular Basis of RNA Interference with Single Molecule Fluorescence)
In the central dogma of molecular biology, RNA was traditionally viewed as a passive information carrier. Recent groundbreaking discoveries have changed this paradigm and a group of non-coding RNAs are now recognized as regulators of gene expression. MicroRNA (miRNA) is a...
Programme: FP7-IDEAS-ERC
Record Number: 214058
Last updated on: 2018-01-15
Final Report Summary - DELCANCER (The role of loss-of-heterozygosity in cancer development and progression)
One-fourth of a typical breast cancer genome is affected by chromosome arm deletions. The concomitant loss of multiple genes creates vulnerabilities that are impossible to reveal through the study of individual genes. By genetically engineering human cells to carry large-scale...
Programme: FP7-IDEAS-ERC
Record Number: 214061
Last updated on: 2018-01-15
Final Report Summary - BIOLEAP (Biotechnological optimization of light use efficiency in algae photobioreactors)
New renewable energy source are highly needed to compensate exhausting fossil fuels reserves and reduce greenhouse gases emissions. Some species of algae have an interesting potential as feedstock for the production of fuels, food and bio-based materials. Strong research...
Programme: FP7-IDEAS-ERC
Record Number: 214064
Last updated on: 2018-01-15
Periodic Report Summary 2 - HLA-DR15 IN MS (Functional Role of the HLA-DR15 Haplotype in Multiple Sclerosis)
Autoimmune diseases (AID) such as rheumatoid arthritis, type I diabetes, and multiple sclerosis (MS) affect >4% of Europeans and increase in prevalence. MS leads to central nervous system (CNS) damage in young adults and preferentially in women. A complex genetic trait and...
Programme: FP7-IDEAS-ERC
Record Number: 213803
Last updated on: 2018-01-15
Periodic Report Summary 2 - DARK (Dark matter of the human transcriptome: Functional study of the antisense Long Noncoding RNAs and Molecular Mechanisms of Action)
This proposal sets out to tackle the central questions about the dark side of our genome, representing more thatn 98% of the genome and that remain largely unknown. In particular, we propose to identify an unidentified set of genes non-coding for protein and embedded antisense...
Programme: FP7-IDEAS-ERC
Record Number: 213802
Last updated on: 2018-01-15
Final Report Summary - PLANT CIRES BIOTECH (Functional characterization of plant cellular IRES  in response to abiotic stress and their use as  biotechnological tools)
Plants, as sessile organisms, are constantly exposed to a wide spectrum of stress conditions and are forced to adapt to them in order to complete their life cycle. These environmental stresses, such as heat, drought, high salinity or pathogen attack, severely reduce crop yield...
Programme: FP7-IDEAS-ERC
Record Number: 213793
Last updated on: 2018-01-15
Final Report Summary - TRANSPORTERPGX (Transporter pharmacogenomics – the contribution of transporters to variability in drug response)
Drug therapy is central to the treatment of most diseases. The response to drugs varies widely between individuals. Part of this variability is due to genetic differences between individuals. The TransporterPGx-project aimed to systematically search for functionally...
Programme: FP7-IDEAS-ERC
Record Number: 214069
Last updated on: 2018-01-15
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List retrieved on: 2018-01-22
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