Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 3627
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Periodic Report Summary 2 - EVOLRECOMBADAPT (Recombination in Adaptive Evolution)
The molecular mechanisms that shape genome function during adaptive evolution and species divergence are poorly understood. We aim to explore how meiotic recombination, an essential process of gametogenesis, varies across the genome and among diverging species and influences...
Programme: FP7-IDEAS-ERC
Record Number: 199366
Last updated on: 2017-06-21
Periodic Report Summary 2 - ENDOFUN (The endodermis - unraveling the function of an ancient barrier)
During the 30 months period of this project, we have published a first description of a mutant with a defect in the endodermal barrier (sgn3) (Pfister et al., eLife, 2014) and shown that this mutant has a whole suite of nutrient homeostatic defects, but that a main component...
Programme: FP7-IDEAS-ERC
Record Number: 199516
Last updated on: 2017-06-21
Periodic Report Summary 2 - DYNGENOME (The Dynamics of Genome Processing)
We have advanced our understanding of, helicases, polymerases, and other molecular machines that help to read out and copy our genome. We have addressed three different phases of functioning for these machines: initiation, elongation, and termination. For example, we have...
Programme: FP7-IDEAS-ERC
Record Number: 199508
Last updated on: 2017-06-21
Periodic Report Summary 2 - NIMO (Neural and Immune Orchestrators of Forebrain Wiring)
Brain functioning relies on complex circuits that begin to be established in the embryo by developmental programs which coordinate the assembly of millions of neurons. Such programs can be modulated by environmental signals, as illustrated by the fact that prenatal...
Programme: FP7-IDEAS-ERC
Record Number: 199507
Last updated on: 2017-06-21
Periodic Report Summary 2 - MYODYN (Myosins and the dynamics of intracellular membranes)
The goal of our project is to better understand the molecular mechanisms that underlie transport events occurring at the level of Golgi/Trans-Golgi network/endosomes in eukaryotic cells. Complex membrane trafficking, still largely unknown, takes place in this region of the...
Programme: FP7-IDEAS-ERC
Record Number: 199505
Last updated on: 2017-06-21
Periodic Report Summary 2 - MYELOSHOCK (Role of myeloid cells, their mediators and their antibody receptors in allergic shock (anaphylaxis) using humanized mouse models and clinical samples)
Allergic shock (anaphylaxis) is a life-threatening reaction to allergens (food, drugs, pollens, venom, etc) occurring in individuals that produce particular antibodies against these allergens. Project MyeloSHOCK aims at unraveling the parameters that control anaphylaxis using...
Programme: FP7-IDEAS-ERC
Record Number: 199500
Last updated on: 2017-06-21
Periodic Report Summary 2 - CHAMELEON (Cellular Hypoxia Alters DNA MEthylation through Loss of Epigenome OxidatioN)
The early causes of cancer are well-known: due to chance or carcinogenic factors, a single cell’s DNA mutates, followed by a rapid expansion of the abnormal cell. These genetic mutations disturb the normal cell function, but are beneficial for the growth and survival of...
Programme: FP7-IDEAS-ERC
Record Number: 199496
Last updated on: 2017-06-21
Periodic Report Summary 2 - MAREFRAME (Co-creating Ecosystem-based Fisheries Management Solutions)
Project Context and Objectives: MareFrame seeks to increase the use of an ecosystem-based approach to fisheries management (EAFM) for better governance in European fisheries. The importance of such an approach has been highlighted by many international organizations (including...
Programme: FP7-KBBE
Record Number: 199548
Last updated on: 2017-06-21
Periodic Report Summary 2 - INTRASPACE (An intracellular approach to spatial coding in the hippocampus)
Humans as many other animals from birds to insects are able to orient themselves and navigate in familiar environments. This ability is thought to rely on the activity of cells in the hippocampal formation, an ensemble of brain structures in the medial temporal lobe in humans...
Programme: FP7-IDEAS-ERC
Record Number: 199494
Last updated on: 2017-06-21
Periodic Report Summary 2 - MECHANODEVO (Mechanical signals in plants: from cellular mechanisms to growth coordination and patterning)
In “On growth and forms” (1917), D’Arcy Thompson stresses the inevitable interactions between physics and biology. Thanks to ongoing developments in live imaging and modeling, this field of study has been rejuvenated: the relation between mechanics and shape changes can...
Programme: FP7-IDEAS-ERC
Record Number: 199492
Last updated on: 2017-06-21
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List retrieved on: 2017-07-20
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