Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 4349
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Specificity of translational control during unfolded protein response
ID: 617837
Start date: 2014-03-01, End date: 2019-02-28
Unfolded protein response (UPR) is activated by multiple types of cellular stress, and can promote either cell survival or apoptosis. The balance between these opposing outcomes is delicately regulated, and when lost, contributes to diverse diseases. UPR enables cells to halt...
Programme: FP7-IDEAS-ERC
Record Number: 185675
Last updated on: 2017-10-06
Amyloid fibril cytotoxicity: new insights from novel approaches
ID: 322408
Start date: 2013-05-01, End date: 2019-04-30
Despite the discovery of amyloidosis more than a century ago, the molecular and cellular mechanisms of these devastating human disorders remain obscure. In addition to their involvement in disease, amyloid fibrils perform physiological functions, whilst others have potentials...
Programme: FP7-IDEAS-ERC
Record Number: 107060
Last updated on: 2017-10-06
Cell cycle regulation of ES cell identity and reprogramming potential
ID: 294627
Start date: 2012-05-01, End date: 2017-04-30
Pluripotent embryonic stem (ES) and germ (EG) cells differ from other stem cells in several respects. They display a characteristically ‘compressed’ cell cycle in which G1 is shortened, contain a high proportion of cells in DNA synthesis (S)-phase and lack several cell cycle ...
Programme: FP7-IDEAS-ERC
Record Number: 102958
Last updated on: 2017-10-06
3to4: Converting C3 to C4 photosynthesis for sustainable agriculture
ID: 289582
Start date: 2012-01-01, End date: 2016-12-31
Most plants use the C3 pathway of photosynthesis that is compromised by gross inefficiencies in CO2 fixation. However, some plants use a super-charged photosynthetic mechanism called C4 photosynthesis. The C4 pathway is used by the most productive vegetation and crops on Eart...
Programme: FP7-KBBE
Record Number: 101753
Last updated on: 2017-10-06
Improving the resistance of legume crops to combined abiotic and biotic stress
ID: 289562
Start date: 2012-01-01, End date: 2016-12-31
ABSTRESS applies combined, integrated systems biology and comparative genomics approaches to conduct a comprehensive study of the gene networks implicated in the interaction of drought stress and Fusarium infection in legumes. It uses Medicago truncatula as a model to rapidly...
Programme: FP7-KBBE
Record Number: 101334
Last updated on: 2017-10-06
European stem cell consortium for neural cell replacement, reprogramming and functional brain repair
ID: 602278
Start date: 2013-10-01, End date: 2017-09-30
Neurostemcellrepair aims at taking human stem cells through the final steps toward clinical application in cell replacement therapy for neurological disorders. PD will be taken as the prototypical disease because stem cell therapy is now close to clinical translation. Moreove...
Programme: FP7-HEALTH
Record Number: 110638
Last updated on: 2017-09-24
Protection against reactive oxygen species in neurodegeneration
ID: 311394
Start date: 2013-02-01, End date: 2018-05-31
Oxidative stress (OS) is implicated in the pathogenesis of some of the most devastating neurological diseases. Therefore, identification of pathways that counteract oxidative damage may lead to therapeutic strategies applicable to a wide range of disorders. I have recently id...
Programme: FP7-IDEAS-ERC
Record Number: 106704
Last updated on: 2017-09-24
Molecular Mechanisms of GABAergic synapse formation: spatial segregation in cortical inhibitory inputs
ID: 310021
Start date: 2013-01-01, End date: 2018-06-30
Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in Science. Und...
Programme: FP7-IDEAS-ERC
Record Number: 105616
Last updated on: 2017-09-24
Development and Demonstration of Highly Insulating, Construction Materials from Bio-derived Aggregates
ID: 636835
Start date: 2015-02-01, End date: 2019-01-31
The ISOBIO project will develop a new approach to insulating materials through the novel combination of existing bio-derived aggregates with low embodied carbon with innovative binders to produce durable composite construction materials. These novel composites will target 50%...
Programme: H2020-EU.
Record Number: 193427
Last updated on: 2017-09-11
Endosomal dependent transport to the unique secretory organelles of apicomplexan parasites
ID: 309255
Start date: 2013-02-01, End date: 2019-01-31
Apicomplexan parasites invade the host cell in an active process that involves gliding motility, formation and movement through the moving junction (MJ) and establishment of a prasitophorous vacuole (PV) around the parasite. In order to invade the host cell they employ an ars...
Programme: FP7-IDEAS-ERC
Record Number: 105401
Last updated on: 2017-09-10
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List retrieved on: 2017-11-19
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