Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 5114
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Specificity of translational control during unfolded protein response
ID: 617837
Start date: 2014-03-01, End date: 2019-02-28
Unfolded protein response (UPR) is activated by multiple types of cellular stress, and can promote either cell survival or apoptosis. The balance between these opposing outcomes is delicately regulated, and when lost, contributes to diverse diseases. UPR enables cells to halt...
Programme: FP7-IDEAS-ERC
Record Number: 185675
Last updated on: 2017-10-06
Biophysical networks underlying the robustness of neuronal excitability
ID: 616827
Start date: 2014-05-01, End date: 2019-04-30
The mammalian nervous system is in some respect surprisingly robust to perturbations, as suggested by the virtually complete recovery of brain function after strokes or the pre-clinical asymptomatic phase of Parkinson’s disease. Ultimately though, cognitive and behavioral rob...
Programme: FP7-IDEAS-ERC
Record Number: 189835
Last updated on: 2017-10-06
Single Molecule Investigations in Living E. coli
ID: 616047
Start date: 2014-04-01, End date: 2019-03-31
The overall ambition is to make intracellular measurements that bridge the gap between quantitative physical models and biological observations, in order to identify and resolve inconsistencies in our current understanding of life at the molecular level. We are particularly i...
Programme: FP7-IDEAS-ERC
Record Number: 185615
Last updated on: 2017-10-06
Morphogenesis of proliferative epithelial tissue
ID: 340784
Start date: 2014-03-01, End date: 2019-08-31
Shape is a conspicuous and fundamental property of living multicellular organisms. Questions related to embryo shape or morphogenesis have naturally haunted developmental biologists for decades. Recent advances have highlighted that the understanding of the morphogenesis of p...
Programme: FP7-IDEAS-ERC
Record Number: 185437
Last updated on: 2017-10-06
Structure function and pharmacology of calcium-activated chloride channels: Anoctamins and Bestrophins
ID: 339116
Start date: 2014-02-01, End date: 2020-01-31
Calcium-activated chloride channels (CaCCs) play key roles in a range of physiological processes such as the control of membrane excitability, photoreception and epithelial secretion. Although the importance of these channels has been recognized for more than 30 years their m...
Programme: FP7-IDEAS-ERC
Record Number: 110412
Last updated on: 2017-10-06
Amyloid fibril cytotoxicity: new insights from novel approaches
ID: 322408
Start date: 2013-05-01, End date: 2019-04-30
Despite the discovery of amyloidosis more than a century ago, the molecular and cellular mechanisms of these devastating human disorders remain obscure. In addition to their involvement in disease, amyloid fibrils perform physiological functions, whilst others have potentials...
Programme: FP7-IDEAS-ERC
Record Number: 107060
Last updated on: 2017-10-06
Following the Genomic Footprints of Early Europeans
ID: 311413
Start date: 2012-10-01, End date: 2017-09-30
Two of greatest challenges of the post-genomic era are to (i) develop a detailed understanding of the heritable variation in the human genome, and to (ii) determine which key events in human evolutionary history that are responsible for patterns of genomic variation. The rece...
Programme: FP7-IDEAS-ERC
Record Number: 105331
Last updated on: 2017-10-06
Solving an evolutionary jigsaw puzzle: A next-generation genomics approach to trace the origins of the eukaryotic cell
ID: 310039
Start date: 2012-11-01, End date: 2017-10-31
The origin of the eukaryotic cell represents an enigmatic yet dramatically incomplete evolutionary puzzle. The few pieces of this puzzle that we have managed to identify thus far indicate that the eukaryotic cell most probably emerged via a fusion of an archaeal and an alphap...
Programme: FP7-IDEAS-ERC
Record Number: 105594
Last updated on: 2017-10-06
Microbial opsins for mammalian vision: Optogenetics in the retina
ID: 309776
Start date: 2012-12-01, End date: 2018-11-30
The retina – a thin sheet of neural tissue in the back of the eye – is a sophisticated image processor which analyzes the incoming light pattern through a set of separate spatio-temporal channels and relays this information to the brain. The loss of the visual sense due to re...
Programme: FP7-IDEAS-ERC
Record Number: 106060
Last updated on: 2017-10-06
Cell cycle regulation of ES cell identity and reprogramming potential
ID: 294627
Start date: 2012-05-01, End date: 2017-04-30
Pluripotent embryonic stem (ES) and germ (EG) cells differ from other stem cells in several respects. They display a characteristically ‘compressed’ cell cycle in which G1 is shortened, contain a high proportion of cells in DNA synthesis (S)-phase and lack several cell cycle ...
Programme: FP7-IDEAS-ERC
Record Number: 102958
Last updated on: 2017-10-06
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List retrieved on: 2017-11-17
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