Results 1 - 10 of 3235
[PROJECT] SHEV - Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines
ID: 280829
Start date: 2012-01-01, End date: 2016-12-31
The impact of HIV/AIDS on world healthcare is tremendous, particularly in the Third World. To curtail the HIV epidemic a cheap and effective vaccine is urgently needed, but despite massive research efforts no vaccine is available yet. Although most vaccines work by inducing n...
Programme: FP7-IDEAS-ERC
Record Number: 102000
Last updated on: 2017-07-12
[PROJECT] CRYOPRESERVATION - Improved Cryopreservation using Ice Binding Proteins
ID: 281595
Start date: 2011-11-01, End date: 2016-10-31
Several organisms have evolved specialized ice binding proteins (IBPs) that prevent their body fluids from freezing (antifreeze proteins, AFPs), inhibit recrystallization of ice in frozen tissues, or initiate freezing at moderate supercooling temperatures (ice nucleating prot...
Programme: FP7-IDEAS-ERC
Record Number: 101006
Last updated on: 2017-07-02
[PROJECT] SUMORICE - SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress
ID: 310235
Start date: 2013-04-01, End date: 2019-03-31
"To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the ...
Programme: FP7-IDEAS-ERC
Record Number: 107495
Last updated on: 2017-06-21
[PROJECT] OSTEOMOTION - OsteoMotion: Analyzing the mechanisms and role of osteogenic cell movement in bone development and disease
ID: 282131
Start date: 2011-11-01, End date: 2016-10-31
Bone development and homeostasis must incontestably rely on a correct spatial positioning of osteoblasts to generate bone at appropriate sites. A failure of osteoblasts to reach the sites in need of bone formation may contribute to impaired fracture repair and osteoporosis. C...
Programme: FP7-IDEAS-ERC
Record Number: 100905
Last updated on: 2017-06-21
[PROJECT] MAGNETOGENETICS - Reverse engineering the vertebrate molecular machinery for magnetic biomineralisation
ID: 311552
Start date: 2013-01-01, End date: 2017-12-31
In order to understand distributed biological networks and invent effective molecular therapies, we need to be able to image and control molecular processes across entire live organisms. Although an arsenal of genetically encoded fluorescent sensors and light-activated protei...
Programme: FP7-IDEAS-ERC
Record Number: 106439
Last updated on: 2017-06-12
[PROJECT] CM TURNOVER - Uncovering the Mechanisms of Cardiomyocyte Differentiation and Dedifferentiation
ID: 281289
Start date: 2012-01-01, End date: 2016-12-31
The quest to restore damaged organs is one of the major challenges in medicine. Recent studies in both animals and in humans suggest that the heart has a limited capacity to replenish its own cardiomyocytes (CMs) throughout life, albeit inadequate to compensate for major inju...
Programme: FP7-IDEAS-ERC
Record Number: 102114
Last updated on: 2017-06-12
[PROJECT] HEMIBIO - HEPATIC MICROFLUIDIC BIOREACTOR
ID: 266777
Start date: 2011-01-01, End date: 2015-12-31
The goal of HeMiBio is to develop a hepatic microfluidic bioreactor from human iPSC-derived hepatocytes, hepatic sinusoidal endothelial cells (HSEC) and stellate cells (HSC), suitable for inclusion in a repeated dose toxicity testing strategy of pharmaceuticals/cosmetic ingre...
Programme: FP7-HEALTH
Record Number: 105662
Last updated on: 2017-06-12
[PROJECT] MALMASQ - Understanding immune evasion by malaria parasites
ID: 615412
Start date: 2014-06-01, End date: 2020-05-31
"The deadliest form of human malaria is caused by the protozoan parasite, Plasmodium falciparum, which annually infects millions worldwide. Its virulence is attributed to its ability to evade the human immune system, by modifying the host red blood cell surface to adhere to t...
Programme: FP7-IDEAS-ERC
Record Number: 185589
Last updated on: 2017-06-05
[PROJECT] PROLONGBILESIGNALING - Improving Metabolism via Prolonged Bile Acid Signalling
targeting hepatic bile acid uptake to fight metabolic diseases
ID: 337479
Start date: 2013-12-01, End date: 2018-11-30
Bile acids play a pivotal role in energy supply as they facilitate the solubilization and absorption of fat in the intestine. Furthermore, bile acids are recently identified as important signalling molecules regulating glucose metabolism, inflammation and energy expenditure. ...
Programme: FP7-IDEAS-ERC
Record Number: 110777
Last updated on: 2017-06-05
[PROJECT] PROMINENT - Progression factors in melanoma leading to novel therapeutic targets
ID: 282059
Start date: 2012-02-01, End date: 2017-01-31
Presently, there is little hope of cure for patients with metastatic melanoma. Greater insight into the molecular and cellular biology of melanoma and the immune response mounted against it is required to indicate new therapeutic approaches. We have created zebrafish models f...
Programme: FP7-IDEAS-ERC
Record Number: 100667
Last updated on: 2017-06-05
List retrieved on: 2017-07-18
