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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 21 - 30 of 10059
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Identify novel pathways to enhance the induction of protective CD8+ T cell responses
ID: 337043
Start date: 2013-10-01, End date: 2018-09-30
There is an urgent need for progress in developing prophylactic and therapeutic vaccination strategies that induce polyfunctional, strongly protective cytotoxic CD8 T cell responses. These could shield us from pathogens against which the presently available, neutralizing anti...
Programme: FP7-IDEAS-ERC
Record Number: 110208
Last updated on: 2017-09-24
The RNA bridge between IRE-1 and PKR leading to metaflammation: discovery and intervention in atherosclerosis
ID: 336643
Start date: 2014-01-01, End date: 2018-06-30
A close functional and molecular integration between metabolic and immune systems is crucial for systemic homeostasis and its’ deregulation is causally linked to obesity and associated diseases including insulin resistance, diabetes and atherosclerosis and known as cardiometa...
Programme: FP7-IDEAS-ERC
Record Number: 110527
Last updated on: 2017-09-24
Metabolic requirements for prostate cancer cell fitness
ID: 336343
Start date: 2013-11-01, End date: 2019-10-31
The actual view of cellular transformation and cancer progression supports the notion that cancer cells must undergo metabolic reprogramming in order to survive in a hostile environment. This field has experienced a renaissance in recent years, with the discovery of cancer ge...
Programme: FP7-IDEAS-ERC
Record Number: 110234
Last updated on: 2017-09-24
Genetics and epigenetics of animal welfare
ID: 322206
Start date: 2013-03-01, End date: 2018-02-28
Animal welfare is a topic of highest societal and scientific priority. Here, I propose to use genomic and epigenetic tools to provide a new perspective on the biology of animal welfare. This will reveal mechanisms involved in modulating stress responses. Groundbreaking aspect...
Programme: FP7-IDEAS-ERC
Record Number: 107325
Last updated on: 2017-09-24
Protection against reactive oxygen species in neurodegeneration
ID: 311394
Start date: 2013-02-01, End date: 2018-05-31
Oxidative stress (OS) is implicated in the pathogenesis of some of the most devastating neurological diseases. Therefore, identification of pathways that counteract oxidative damage may lead to therapeutic strategies applicable to a wide range of disorders. I have recently id...
Programme: FP7-IDEAS-ERC
Record Number: 106704
Last updated on: 2017-09-24
Proliferation and Migration under External Constraints
ID: 311205
Start date: 2013-01-01, End date: 2018-06-30
Cell proliferation lies at the heart of the threat posed by tumours. It involves cellular growth, division and migration. The tissue surrounding a tumor physically limits its proliferation, which implies that cells that are able to produce effective tumour growth, as well as ...
Programme: FP7-IDEAS-ERC
Record Number: 106353
Last updated on: 2017-09-24
Anatomical and Functional Dissection of Neural Circuits in the Zebrafish Optic Tectum
ID: 311159
Start date: 2013-01-01, End date: 2018-06-30
The optic tectum has emerged as a tractable visuomotor transformer, in which anatomical and functional studies can allow a better understanding of how behavior is controlled by neuronal circuits. We plan to examine the formation and function of the visual system in zebrafish ...
Programme: FP7-IDEAS-ERC
Record Number: 106304
Last updated on: 2017-09-24
Molecular Mechanisms of GABAergic synapse formation: spatial segregation in cortical inhibitory inputs
ID: 310021
Start date: 2013-01-01, End date: 2018-06-30
Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in Science. Und...
Programme: FP7-IDEAS-ERC
Record Number: 105616
Last updated on: 2017-09-24
Dissecting genotype-phenotype relationships using high-throughput genomics and carefully selected study populations
ID: 294601
Start date: 2012-05-01, End date: 2017-04-30
A major aim in genome research is to reveal how genetic variation affects phenotypic variation. Here I propose to use high-throughput genomics (whole genome sequencing, transcriptome and epigenome analysis) to screen carefully selected study populations where the chances are ...
Programme: FP7-IDEAS-ERC
Record Number: 103577
Last updated on: 2017-09-24
Sequence based strategies to identify genetic variation associated with mental retardation and schizophrenia
ID: 282330
Start date: 2012-08-01, End date: 2017-07-31
Mental retardation (MR) and schizophrenia (SCZ) are disorders of the brain that affect 2-3% and 1% of the population, respectively. Both disorders are considered to be highly heritable, but exhibit heterogeneous genetic etiology. Recent genetic studies have led to discoveries...
Programme: FP7-IDEAS-ERC
Record Number: 104206
Last updated on: 2017-09-24
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List retrieved on: 2017-11-18
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