Results 1 - 10 of 108
[PROJECT] TX-FACTORS - NEW BIOLOGICAL FUNCTIONS AND THERAPEUTIC POTENTIAL OF
VASCULAR ENDOTHELIAL GROWTH FACTORS
ID: 268804
Start date: 2011-06-01, End date: 2016-05-31
This application promises to provide new treatment options for cancer and cardiovascular diseases that are the leading causes of morbidity and mortality in the western world. Current cardiovascular and cancer therapies are often insufficient, unsuccessful or not suitable for ...
Programme: FP7-IDEAS-ERC
Record Number: 99210
Last updated on: 2017-06-26
[PROJECT] O-PTM-BIOMARKERS - Discovery of novel cancer serum biomarkers based on aberrant post translational modifications of O-glycoproteins (O-PTM-Biomarkers) and their application to early detection of cancer
ID: 201381
Start date: 2008-01-01, End date: 2011-03-31
Early detection accomplished through an efficient screening programme remains the most promising approach to improve the long-term survival of cancer patients. Therefore there is a pressing need for the development of biomarkers, which detect the early changes for cancers whe...
Programme: FP7-HEALTH
Record Number: 88179
Last updated on: 2017-05-30
[PROJECT] REGENERATIVETHERAPY - Cell and gene therapy approaches for inherited diseases with unsatisfying or no therapeutic option
ID: 269037
Start date: 2011-10-01, End date: 2016-09-30
We have developed the tools and experimental models and have provided the proof of principle that gene modified autologous haematopoietic stem cells can restore a complete immunological system in vivo in a particular form of SCID. We are pursuing these efforts applying this s...
Programme: FP7-IDEAS-ERC
Record Number: 99939
Last updated on: 2017-05-29
[PROJECT] BREATHE - BRain dEvelopment and Air polluTion ultrafine particles in scHool childrEn
ID: 268479
Start date: 2011-08-01, End date: 2016-07-31
Traffic-related air pollution is an important environmental problem that may affect neurodevelopment. Ultrafine particles (UFP) translocate to the brains of experimental animals resulting in local proinflammatory overexpression. As the basic elements for thinking are acquired...
Programme: FP7-IDEAS-ERC
Record Number: 99632
Last updated on: 2017-05-29
[PROJECT] HYGIENE - THE HYGIENE HYPOTHESIS : REVISITING THE CONCEPT BY INTEGRATING EPIDEMIOLOGY AND MECHANISTIC STUDIES
ID: 250290
Start date: 2010-08-01, End date: 2015-07-31
The hygiene hypothesis postulating the paradoxical protective role of infections on immune-mediated diseases including atopy (i.e. atopic dermatitis, rhinitis, asthma) and more recently autoimmune diseases has been the matter of extensive investigation. The aim of the present...
Programme: FP7-IDEAS-ERC
Record Number: 95354
Last updated on: 2017-05-29
ID: 250277
Start date: 2010-05-01, End date: 2015-04-30
The goal of this project is to provide, to the large community of scientist working in molecular target therapies, a fast and accurate tool capable of obtaining an atomic detailed mechanism of the protein-ligand induced fit, of its recognition process and of the ligand migrat...
Programme: FP7-IDEAS-ERC
Record Number: 94346
Last updated on: 2017-05-29
[PROJECT] TREATSKIN - Tissue engineering to evaluate novel treatments for skin cancer and genetic disease
ID: 250170
Start date: 2010-05-01, End date: 2015-04-30
As our understanding of disease translates from basic science to clinical application there is a need for robust preclinical models to test interventions and therapies, which mirror the clinical situation and likely outcomes. This will assist key stage decision making before ...
Programme: FP7-IDEAS-ERC
Record Number: 94441
Last updated on: 2017-05-29
[PROJECT] PREVENTRA - Genes, environment and immunity in the pathogenesis of rheumatoid arthritis
ID: 250167
Start date: 2010-04-01, End date: 2016-03-31
Aims and significance: The aims of this program are (1) To obtain new understanding of how environmental and life style factors interact with genes to induce immune reactions able to cause the different forms of arthritis that are defined as RA; (2) To use this understanding ...
Programme: FP7-IDEAS-ERC
Record Number: 94242
Last updated on: 2017-05-29
[PROJECT] FLUPLAN - Novel strategies to combat future influenza pandemics
ID: 250136
Start date: 2010-06-01, End date: 2015-05-31
The Mexican influenza A virus (H1N1) reminds us that the threat of an influenza pandemic is real. The 1918 Spanish flu virus, also started as a low pathogenic virus that mutated into a highly pathogenic virus within months, causing more than 50 million deaths. The Mexican inf...
Programme: FP7-IDEAS-ERC
Record Number: 94581
Last updated on: 2017-05-29
ID: 250124
Start date: 2010-04-01, End date: 2015-03-31
A foremost health problem stems from the burden of degenerative diseases, including heart failure, neurodegeneration, retinal degeneration and diabetes, essentially linked to the aging of the human population and the incapacity of post-mitotic tissues to undergo efficient rep...
Programme: FP7-IDEAS-ERC
Record Number: 94239
Last updated on: 2017-05-29
List retrieved on: 2017-07-15
