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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 5779
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Positioning the nucleus for cell migration and muscle fiber function
ID: 617676
Start date: 2014-07-01, End date: 2019-06-30
The cell nucleus is positioned at specific places within the cytoplasm and this position is important for different cellular, developmental and physiological processes. Nuclear positioning depends on connections between nuclear envelope proteins and the cytoskeleton. In migra...
Programme: FP7-IDEAS-ERC
Record Number: 189851
Last updated on: 2017-11-20
Genetic/epigenetic basis of ethnic differences in cancer predisposition
ID: 340588
Start date: 2014-02-01, End date: 2020-01-31
"Integration of large scale genetic and epigenetic analysis needs to be coupled with well defined biological hypotheses that can be experimentally tested. This project is aimed at developing a novel integrated approach to understand genetic and epigenetic predisposition to ca...
Programme: FP7-IDEAS-ERC
Record Number: 110855
Last updated on: 2017-11-20
Directed evolution of a synthetic episome based on hexitol nucleic acids (HNA)
ID: 336936
Start date: 2014-02-01, End date: 2019-01-31
A long term goal of synthetic biology is the assembly of a cell from its individual components. A genetic element based on synthetic nucleic acids capable of stable propagation, a synthetic episome, is the minimal genetic element required for the systematic development of all...
Programme: FP7-IDEAS-ERC
Record Number: 111023
Last updated on: 2017-11-20
Intracellular antibody Immunity
ID: 281627
Start date: 2012-01-01, End date: 2016-12-31
Antibodies are a critical component of immune defence but they provide purely extracellular protection – once inside a cell, a pathogen is safe. This is the view of humoral immunity that has existed for over 100 years. However, recent work in my lab has led to the discovery o...
Programme: FP7-IDEAS-ERC
Record Number: 100264
Last updated on: 2017-11-20
Individualized early risk assessment for heart diseases
ID: 340248
Start date: 2014-06-01, End date: 2019-05-31
Heart failure (HF) is the common end-stage of different medical conditions. It is the only growing cardiovascular disease and its prognosis remains worse than that of many malignancies. The lack of evidence-based treatment for patients with diastolic HF (HFpEF) exemplifies th...
Programme: FP7-IDEAS-ERC
Record Number: 188503
Last updated on: 2017-11-20
Development and application of global lipidomic arrays to inflammatory vascular disease
ID: 339129
Start date: 2014-02-01, End date: 2019-01-31
How lipids are regulated on a global scale during vascular inflammation is not known. Thus, a major challenge exists to describe and catalog the total lipidome, in particular enabling the identification of new biologically active lipids, and description of changes. This is an...
Programme: FP7-IDEAS-ERC
Record Number: 111069
Last updated on: 2017-11-20
Randomized controlled trial of metformin and dietary restriction to prevent age-related morbid events in people with  metabolic syndrome
ID: 322752
Start date: 2013-08-01, End date: 2019-07-31
Age–related chronic diseases (ArCD) are complex non-linear processes that depends on a large number of interconnected genetic and metabolic pathways which should be tackled with a many faceted preventive strategy. Calorie-dense diet and sedentary lifestyle are responsible of ...
Programme: FP7-IDEAS-ERC
Record Number: 108844
Last updated on: 2017-11-20
A New Paradigm for Public Health Surveillance: Unlocking the Potential of Data to Empower Women and Health Systems
ID: 617639
Start date: 2014-09-01, End date: 2019-08-31
Rationale: State of the art health registries, cornerstones of public health surveillance, have hardly capitalized on the information and communication technology revolution. Many continue to be static, fragmented, and passive data repositories disseminating outdated reports ...
Programme: FP7-IDEAS-ERC
Record Number: 192003
Last updated on: 2017-11-20
Light-driven Chemical Synthesis using Cytochrome P450s
ID: 323034
Start date: 2013-03-01, End date: 2019-02-28
The goal of this proposed research initiative is to engineer chloroplasts into production units for high value bio-active natural products. The first aim is to re-route the biosynthetic pathways for these compounds into the chloroplast and to boost compound formation by optim...
Programme: FP7-IDEAS-ERC
Record Number: 107068
Last updated on: 2017-11-20
Identification and targeting of somatic changes initiating sporadic cancers
ID: 322602
Start date: 2013-03-01, End date: 2018-02-28
Cancer drugs are extremely ineffective, generally because current therapies do not address cellular heterogeneity. While hypothesis-driven research and functional genomics identify ever more novel putative therapeutic targets, the scientific community lacks rationales to atta...
Programme: FP7-IDEAS-ERC
Record Number: 107221
Last updated on: 2017-11-20
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List retrieved on: 2017-11-24
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