Results 1 - 10 of 405
[PROJECT] RATHER - Rational Therapy for Breast Cancer: Individualized Treatment for Difficult-to-Treat Breast Cancer Subtypes
ID: 258967
Start date: 2011-01-01, End date: 2018-06-30
Cancer genotyping has identified a number of correlations between mutations in specific genes and responses to targeted anti-cancer drugs, with many mutations occurring in kinases or downstream signaling components. While there are several ongoing large-scale genome re-sequen...
Programme: FP7-HEALTH
Record Number: 97660
Last updated on: 2017-07-16
[PROJECT] EUTRAF - The European Network for Translational Research in Atrial Fibrillation
ID: 261057
Start date: 2010-11-01, End date: 2015-10-31
The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular ...
Programme: FP7-HEALTH
Record Number: 96749
Last updated on: 2017-07-12
[PROJECT] IDEAL - Integrated research on DEvelopmental determinants of Aging and Longevity
ID: 259679
Start date: 2011-02-01, End date: 2016-01-31
IDEAL will obtain insight into the role of early life conditions affecting late-life health, disease and aging, and the role of epigenetic regulation therein. IDEAL will identify the determinants and targets of this epigenetic regulation utilizing a resource of unique human c...
Programme: FP7-HEALTH
Record Number: 98424
Last updated on: 2017-07-12
[PROJECT] METOXIA - Metastatic tumours facilitated by hypoxic tumour micro-environments
ID: 222741
Start date: 2009-02-01, End date: 2014-07-31
Recent research suggests that the hypoxic micro-environment of tumours is one of the major drivers of metastatic spread of cancer. Furthermore, hypoxic tumour micro-environments may result in treatment resistance of cancer cells, therefore causing a double effect of reducing ...
Programme: FP7-HEALTH
Record Number: 91061
Last updated on: 2017-07-12
[PROJECT] CRYOPRESERVATION - Improved Cryopreservation using Ice Binding Proteins
ID: 281595
Start date: 2011-11-01, End date: 2016-10-31
Several organisms have evolved specialized ice binding proteins (IBPs) that prevent their body fluids from freezing (antifreeze proteins, AFPs), inhibit recrystallization of ice in frozen tissues, or initiate freezing at moderate supercooling temperatures (ice nucleating prot...
Programme: FP7-IDEAS-ERC
Record Number: 101006
Last updated on: 2017-07-02
[PROJECT] STOPENTERICS - Vaccination against Shigella and ETEC: novel antigens, novel approaches
ID: 261472
Start date: 2010-11-01, End date: 2017-12-31
To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunit...
Programme: FP7-HEALTH
Record Number: 97173
Last updated on: 2017-07-02
[PROJECT] ACADEMIC GMP - The impact of Regulation (EC) No 1394/2007 on the development of Advanced Therapy Medicinal Products (ATMPs): an academic perspective
ID: 260773
Start date: 2010-09-01, End date: 2013-05-31
Advanced Therapy Medicinal Products (ATMPs) are medicinal products for human use, based on gene therapy, somatic cell therapy or tissue engineering. A rapidly growing area in translational research, they represent the ‘next generation’ of complex medicines for complex disease...
Programme: FP7-HEALTH
Record Number: 96783
Last updated on: 2017-07-02
[PROJECT] THE METAENDOMATRIX - THE ENDOCYTIC AND CYTOSKELETAL MATRIX IN THE PLASTICITY OF TUMOR CELL INVASION AND MIGRATION
ID: 268836
Start date: 2011-08-01, End date: 2016-07-31
"Tumor cells can adopt different modes of cell motility. The ability to switch between diverse modes of migration enables tumors to adapt to micro-environmental conditions and to metastasize. The critical pathways and cellular processes underlying the plasticity of tumor cell...
Programme: FP7-IDEAS-ERC
Record Number: 99566
Last updated on: 2017-06-26
[PROJECT] DECIDE - Developing and Evaluating Communication strategies to support Informed Decisions and practice based on Evidence
ID: 258583
Start date: 2011-01-01, End date: 2015-12-31
Objective: To improve the dissemination of evidence-based recommendations by building on the work of the GRADE Working Group to develop and evaluate methods that address the targeted dissemination of guidelines. Background: Healthcare decision makers face challenges in unders...
Programme: FP7-HEALTH
Record Number: 97693
Last updated on: 2017-06-26
[PROJECT] SUMORICE - SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress
ID: 310235
Start date: 2013-04-01, End date: 2019-03-31
"To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the ...
Programme: FP7-IDEAS-ERC
Record Number: 107495
Last updated on: 2017-06-21
List retrieved on: 2017-08-02
