Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS

CORDIS reúne toda la información sobre los proyectos financiados por Horizonte 2020 , y ahora también resúmenes de los informes relacionados. Se puede descargar toda la documentación de estos proyectos en el Portal de datos abiertos de la UE .

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Results 1 - 10 of 11425
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Mid-Term Report Summary - POPRNASEQ (Population transcriptional genomics in humans using high throughput sequencing)
In the first 2.5 years of the projects, our work has advanced well and we have achieved many of the goals originally set for the project. We have dissected the relationships and learned many of the properties of genetic and epigenetic variation and how the two together...
Programme: FP7-IDEAS-ERC
Record Number: 180500
Last updated on: 2016-04-15
Population transcriptional genomics in humans using high throughput sequencing
ID: 260927
Fecha de inicio: 2011-05-01, Fecha de finalización: 2016-04-30
Gene expression is one of the marks of cellular state and function. The relative abundance of transcripts defines and is a result of the differentiation status of a cell. Interrogation of gene expression levels and patterns in the human and other genomes can be informative ab...
Programme: FP7-IDEAS-ERC
Record Number: 98908
Last updated on: 2016-12-05
Final Report Summary - TRANSINTEG (Transcription and the maintenance of genome integrity)
DNA damage in genes can give rise to harmful mutations but can also obstruct the progress of transcribing RNA polymerase II (RNAPII), thereby affecting gene expression, also at the level of mRNA splicing. Not surprisingly, repair pathways have evolved that specifically target...
Programme: FP7-IDEAS-ERC
Record Number: 189317
Last updated on: 2016-09-16
Transcription and the maintenance of genome integrity
ID: 268797
Fecha de inicio: 2011-05-01, Fecha de finalización: 2016-04-30
Maintaining genome integrity is crucial, especially in protein-encoding genes. DNA damage in genes can give rise to harmful mutations, but it can also directly obstruct the progress of transcribing RNA polymerase II (RNAPII), thereby blocking gene expression. Not surprisingly...
Programme: FP7-IDEAS-ERC
Record Number: 98875
Last updated on: 2016-12-05
Regulating recombination in mitotic and meiotic cells
ID: 268639
Fecha de inicio: 2011-05-01, Fecha de finalización: 2016-04-30
DNA is a highly reactive molecule that is subject to deliberate, spontaneous and environmental damage. One of the most catastrophic lesions in DNA is the double-strand break (DSB), which if left unrepaired can result in cell death, infertility, genome instability and cancer. ...
Programme: FP7-IDEAS-ERC
Record Number: 98874
Last updated on: 2016-12-05
Final Report Summary - RECMITMEI (Regulating recombination in mitotic and meiotic cells)
My lab previously discovered the Fe-S cluster helicase RTEL1 as a key regulator of homologous recombination. We hypothesized that RTEL1 could metabolise D-loop intermediates to influence the outcome of recombination reactions in various different cellular contexts, including...
Programme: FP7-IDEAS-ERC
Record Number: 189276
Last updated on: 2016-09-14
Mid-Term Report Summary - CARDIO-IPS (Induced Pluripotent stem Cells: A Novel Strategy to Study Inherited Cardiac Disorders)
The study of several cardiac genetic disorders is hampered by the lack of suitable in vitro human models. The overarching hypothesis of the current project is that the generation of patient-specific human induced pluripotent stem cells (hiPSCs) can allow the development of...
Programme: FP7-IDEAS-ERC
Record Number: 180508
Last updated on: 2016-04-15
Induced Pluripotent stem Cells: A Novel Strategy to Study Inherited Cardiac Disorders
ID: 260830
Fecha de inicio: 2011-03-01, Fecha de finalización: 2016-02-29
The study of several genetic disorders is hampered by the lack of suitable in vitro human models. We hypothesize that the generation of patient-specific induced pluripotent stem cells (iPSCs) will allow the development of disease-specific in vitro models; yielding new pathoph...
Programme: FP7-IDEAS-ERC
Record Number: 98107
Last updated on: 2016-12-05
Final Report Summary - BRAINSTATES (Brain states, synapses and behaviour)
The first electroencephalogram recordings of electrical activity from the brain of awake animals and humans revealed patterns of spontaneous activity that were correlated to different behavioral states but seemed unrelated to direct sensory input. These patterns of activity...
Programme: FP7-IDEAS-ERC
Record Number: 183491
Last updated on: 2016-06-07
Brain states, synapses and behaviour
[PROYECTO] BRAINSTATES - Brain states, synapses and behaviour
ID: 260590
Fecha de inicio: 2011-02-01, Fecha de finalización: 2016-01-31
Global changes in patterns of neuronal activity or brain state are the first phenomenon recorded in the awake human brain (1). Changes in brain state are present in recordings of neocortical activity from mouse to man. It is now thought that changes in brain state are fundame...
Programme: FP7-IDEAS-ERC
Record Number: 97779
Last updated on: 2016-12-05
12 3 4 5 6 7 8 9 10 > >| 
List retrieved on: 2016-12-07