Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS

CORDIS reúne toda la información sobre los proyectos financiados por Horizonte 2020 , y ahora también resúmenes de los informes relacionados. Se puede descargar toda la documentación de estos proyectos en el Portal de datos abiertos de la UE .

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Results 1 - 10 of 2315
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Mid-Term Report Summary - CUMTAS (Customized Micro Total Analysis Systems to Study Human Phase I Metabolism)
The project aims at developing low-cost microfluidic technology for rapid screening of molecular-level metabolic interactions of environmental and household chemicals with clinically relevant pharmaceuticals. On the basis of the structural resemblance to pharmaceuticals and...
Programme: FP7-IDEAS-ERC
Record Number: 178285
Last updated on: 2016-05-04
Customized Micro Total Analysis Systems to Study Human Phase I Metabolism
ID: 311705
Fecha de inicio: 2013-05-01, Fecha de finalización: 2019-02-28
The goal of this project is to develop inexpensive, high-throughput technology to screen the thus far unexplored metabolic interactions between environmental and household chemicals and clinically relevant drugs. The main influential focus will be on human phase I metabolism ...
Programme: FP7-IDEAS-ERC
Record Number: 106984
Last updated on: 2017-02-27
Signal integration and rewiring during tumor development
ID: 294665
Fecha de inicio: 2012-07-01, Fecha de finalización: 2017-12-31
Cell fate decisions rely on signaling pathways that integrate external signals to coordinate specific intracellular programs. One of these pathways leads to the activation of p38α MAPK, which plays key roles in cell responses to many types of stresses as well as chemotherapeu...
Programme: FP7-IDEAS-ERC
Record Number: 103689
Last updated on: 2017-02-27
Mid-Term Report Summary - P38CANCER (Signal integration and rewiring during tumor development)
Cell fate decisions rely on signaling pathways that integrate external signals to coordinate specific intracellular programs. One of these pathways leads to the activation of the protein kinase p38a, which plays key roles in cell responses to many types of stresses as well as...
Programme: FP7-IDEAS-ERC
Record Number: 179280
Last updated on: 2016-04-27
Final Report Summary - ASSET (ASSET: Analysing and Striking the Sensitivities of Embryonal Tumours)
Executive Summary ASSET applied a systems level approach to study embryonal tumours (ET), which include neuroblastoma (NB), medulloblastoma (MB) and Ewing sarcoma family tumours (ESFT). These tumours arise in babies and children, and are devastating for the patients and their...
Programme: FP7-HEALTH
Record Number: 191744
Last updated on: 2016-11-11
ASSET: Analysing and Striking the Sensitivities of Embryonal Tumours
ID: 259348
Fecha de inicio: 2010-11-01, Fecha de finalización: 2016-04-30
Cancer is hallmarked by multiple genetic aberrations that lead to a functional derangement of cellular signalling networks. Embryonal tumours (ETs) comprising neuroblastoma, medulloblastoma and Ewing sarcoma, occur early in life, and thus may reveal pathogenetically relevant ...
Programme: FP7-HEALTH
Record Number: 97171
Last updated on: 2016-04-11
Transcriptional regulation of endothelial blood brain barrier differentiation by Wnt signaling
ID: 268870
Fecha de inicio: 2011-08-01, Fecha de finalización: 2016-07-31
The brain vasculature has evolved to protect the central nervous system from the constantly changing milieu in the blood stream. Endothelial cells of brain capillaries form the so called blood brain barrier (BBB), an active permeability barrier and transport system which allo...
Programme: FP7-IDEAS-ERC
Record Number: 99546
Last updated on: 2017-01-30
Final Report Summary - WNT FOR BRAIN (Transcriptional regulation of endothelial blood brain barrier differentiation by Wnt signaling)
The brain vasculature has evolved to protect the central nervous system from the constantly changing milieu in the blood stream. Endothelial cells of brain capillaries form the so-called blood brain barrier (BBB), an active permeability barrier and transport system that allows...
Programme: FP7-IDEAS-ERC
Record Number: 191727
Last updated on: 2016-11-11
THE ENDOCYTIC AND CYTOSKELETAL MATRIX IN THE PLASTICITY OF TUMOR CELL INVASION AND MIGRATION
ID: 268836
Fecha de inicio: 2011-08-01, Fecha de finalización: 2016-07-31
"Tumor cells can adopt different modes of cell motility. The ability to switch between diverse modes of migration enables tumors to adapt to micro-environmental conditions and to metastasize. The critical pathways and cellular processes underlying the plasticity of tumor cell...
Programme: FP7-IDEAS-ERC
Record Number: 99566
Last updated on: 2016-03-16
Final Report Summary - THE METAENDOMATRIX (THE ENDOCYTIC AND CYTOSKELETAL MATRIX IN THE PLASTICITY OF TUMOR CELL INVASION AND MIGRATION)
Tumor dissemination to distant site and seeding of metastasis is the major clinical problem in cancer. We aimed to understand the molecular underlying mechanisms through study endocytic networks, which by controlling key steps of intracellular trafficking pathways have a...
Programme: FP7-IDEAS-ERC
Record Number: 191696
Last updated on: 2016-11-11
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List retrieved on: 2017-02-28