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Results 1 - 10 of 31194
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Microbiological survey of DUWS across the EU
Water supplied by 51% of dental units in this general practice survey failed ADA recommendations on microbial load (<200 cfu.ml-1) (Anonymous 2002). Although the absolute microbial numbers reported in this study are lower than those reported elsewhere (Depaola et al. 2002, Ped...
Programme: FP5-LIFE QUALITY
Record Number: 31155
Last updated on: 2003-12-18
Microbial risk assessment of dental unit water systems (duws) in general dental practice (gdp)
ID: QLK4-CT-2000-00097
Data di inizio: 2001-03-01, Termine: 2003-06-30
Little knowledge exists on cross-infection risks from dental unit water systems (DUWS) in general dental practices (GDP), with no guidelines for their safe maintenance. We propose to determine quantitatively microbial contamination odes in GDP in Europe; the role of biofilms i...
Programme: FP5-LIFE QUALITY
Record Number: 59041
Last updated on: 2005-04-12
Use of antimicrobial products to control microbial contamination of DUWS across the EU
Different manufacturers may recommend specific products to be used in their equipment, e.g. because of materials compatibility issues. Therefore, practitioners should consult with the manufacturer of their DUWS prior to introducing any chemical agent, as this may otherwise inv...
Programme: FP5-LIFE QUALITY
Record Number: 31154
Last updated on: 2003-12-18
Questionnaire survey of dentists attitude to microbial contamination of dental unit water systems
This study involved the largest survey of GDP's undertaken in the EU. This involved recruiting 436 GDP's in the UK, Denmark, Germany, The Netherlands, Greece, Spain and Ireland. Of the GDP's recruited 258 (59%) completed and returned their questionnaires. The majority of the D...
Programme: FP5-LIFE QUALITY
Record Number: 31153
Last updated on: 2003-12-18
Classes I and II HLA-restricted new unique and shared cancer antigens
New antigens have been characterized both in melanoma and lung cancer patients. These antigens are restricted either by class I or II HLA and can be recognized by patient's T lymphocytes. These proteins, or their peptides containing the epitope, stimulate the patient's immune...
Programme: FP5-LIFE QUALITY
Record Number: 31151
Last updated on: 2003-12-18
Results of testing disinfectant products in the laboratory model
Dental Unit Water Systems (DUWS) are used in dental practices to provide water to irrigate the oral cavity, and have been demonstrated to be heavily contaminated with micro-organisms, particularly in dental hospitals. There is currently no EU Commission guideline applied to DU...
Programme: FP5-LIFE QUALITY
Record Number: 31152
Last updated on: 2003-12-18
Antigen presentation by chaperon proteins and cd4+ t cell specific help for a new and efficient strategy of cancer vaccination.
ID: QLK3-CT-1999-00064
Data di inizio: 2000-02-01, Termine: 2003-01-31
To identify new HLA-classes I and II restricted antigens (Ags) from human tumours of different histology and to define the role of CD4+ T cells in induction and maintenance of effective cytotoxic T lymphocyte (CTL) responses. To evaluate the role of chaperon proteins, includin...
Programme: FP5-LIFE QUALITY
Record Number: 51666
Last updated on: 2005-04-12
Signal molecules for induction, amplification and persistence of CTL response
We have shown that the 4-1BB molecule expressed by antigen-presenting cells can deliver in vivo a powerful co-stimulatory signal to T cells. This signal was found to replace the need for CD4 + T cell help in stimulating tumour-specific cytotoxic T lymphocytes (CTLs). Triggeri...
Programme: FP5-LIFE QUALITY
Record Number: 31150
Last updated on: 2003-12-18
Molecules and signals that allow gp96 HSPs to present tumor antigens
The heat-shock proteins (HSPs) 96 were shown to mediate maturation of mouse and human dendritic cells (DCs) through the binding of the specific receptors, Toll-like 2 and 4. These proteins were shown to bind also to platelets. Experiments in animal models demonstrated that imm...
Programme: FP5-LIFE QUALITY
Record Number: 31149
Last updated on: 2003-12-18
A new molecule (LAG-3) that induces maturation and activation of DCs
To be effective, a classical vaccine should supply two types of immune signals: an antigen (Ag) and a suitable accessory signal. In fact, recognizing the Agby itself is not sufficient to protect the host; antigen recognition has to elicit a biological response suited to the na...
Programme: FP5-LIFE QUALITY
Record Number: 31148
Last updated on: 2003-12-18
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