Community Research and Development Information Service - CORDIS

FP6

InSilicoTox Project - Deliverable 3 (D3) - (Q)SARs for the Prediction of Reactive Toxicity

Project ID: 42328
Funded under: FP6-MOBILITY

Abstract

Electrophilic reactivity is an important issue to assist in the understanding and description of interactions between xenobiotic toxicants and biochemical macromolecules. An increasing part of developing alternatives for the toxicological assessment of chemicals, including in chemico (experimental measurement of reactivity) and in silico (computational) approaches, involves the understanding of reactive toxicity. It has long been understood that compounds capable of covalent interactions with biological macromolecules are liable to elicit toxic effects.

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Record Number: 10452 / Last updated on: 2010-12-07
Category: PROJ
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