Community Research and Development Information Service - CORDIS


Final Report - CONTICA (Control of Intracellular Calcium in Arrhythmias)

Project ID: 18802


This is the final report for the CONTICA project, and it includes figures and detailed progress of work performed for each work package and their results. In particular, the CONTICA partners have generated the first mouse model of catecholaminergic polymorphic ventricular tachycardia (CPVT) and have elucidated the molecular and cellular mechanisms underlying CPVT in unprecedented detail. Furthermore, by combining the CPVT mouse model with physiological and pathological stimuli, CONTICA has been gaining novel insights also into the development of hypertrophy and heart failure and arrhythmogenesis in these cardiac diseases.

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