Community Research and Development Information Service - CORDIS

FP7

Final Report - ANTIBIOTICS DOS (Diversity oriented synthesis of peptide derivatives as antibiotics)

Project ID: 235295
Funded under: FP7-PEOPLE

Abstract

The aim is to find new antibacterial molecules with novel mechanisms of action, by applying new and innovative approaches in organic and medicinal chemistry, such as diversity-oriented synthesis (DOS) and chemical genetics. Their report includes four images. Figure 1 is of 'General structure of the library compounds', Figure 2 is of the rigified library compounds inspired by the antibiotic piperazinomycin, Schematic 1 is an outline of the B/C/P strategy for the preparation of the target library and Schematic 2 is of pair steps 1,3-dipolar cyclo-addition followed by DKP formation.

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Related information

Record Number: 11638 / Last updated on: 2011-09-21
Category: PROJ