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FP6

Final Report - HDLOMICS (Functional genomics of inborn errors and therapeutic interventions in high density lipoprotein metabolism)

Project ID: 37631
Funded under: FP6-LIFESCIHEALTH

Abstract

This is the final report for the HDLOMICS project which aimed to apply functional genomics approaches including genomics, proteomics and lipidomics as well as new clinical diagnostic tools to study the effects of differential regulation of HDL metabolism on pathophysiological events relevant for atherosclerosis.

The project hopes that the results of the consortium applied with regard to the development of both diagnostics and therapies which ultimately help to reduce morbidity and mortality associated with cardiovascular diseases. In addition, newly identified genes important in HDL metabolism may turn out as important targets for the development of drugs which help to prevent, stop or even cure atherosclerosis. Finally, the project partners expect to develop gene therapy protocols to treat inborn errors of HDL metabolism.

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