Community Research and Development Information Service - CORDIS


Final Report - ENZYMEMBRANE (The study of membrane phenomena caused by sphingomyelinase D from spider venoms)

Project ID: 236688
Funded under: FP7-PEOPLE


Bites from the loxosceles genus, or brown spiders, cause several clinical manifestations in mammals. Their venom has a toxic component with a rare enzymatic activity, termed Sphingomyelinase D (SMD). Nevertheless, the relevant action mechanism remains incompletely understood.

Therefore, the ENZYMEMBRANE project, which was funded under the European Commission's Seventh Framework Programme (FP7), aimed to implement a multidisciplinary strategy to explore the mechanism of SMD action at different molecular and supramolecular levels.

This final activity report provides an overview of the project objectives and the specific scientific questions for which answers were sought. In addition, the document focuses on the various research components and approaches and summarises the obtained results, which are highlighted using a series of characteristic images.

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Record Number: 12566 / Last updated on: 2012-03-14
Category: PROJ