Community Research and Development Information Service - CORDIS


Final Report - GENDEP (Genome-based therapeutic drugs for depression)

Project ID: 503428


This is the final report for the GENDEP project. Although there is abundant evidence for efficacy of antidepressants a substantial minority of patients show an unsatisfactory response, and cessation of medication because of adverse effects is common. The choice of what drug to prescribe for optimal response with minimum unwanted effects is largely a matter of taking an educated guess. Pharmaco-genetics offers considerable potential to provide tools to aid targeted, rational prescribing.

As outlined in their final report, this project enabled European SMEs to work in a collaborative and integrated fashion with leading academic centres and a large industrial partner. The multicentre pan-European collaborative nature of this research project included unique mobilisation of resources and expertise across Europe, in an integrated project that has the power to generate data of high scientific import and to enable sustained pan-European research in this field to be conducted in a manner that will be truly competitive in the international arena.

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