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FP6

Final Report - BINDING GASTRIN (Therapeutic synthetic antibodies -binding bodies- against gastrin to treat Pancreatic Cancer)

Project ID: 512691
Funded under: FP6-SME

Abstract

This is the final report for the BINDING GASTRIN project which proposed to develop high affinity and low cost synthetic antibodies -'binding bodies' - against gastrin. Binding bodies are two or more peptides which represent complementary determining regions (CDRs, which are the hypervariable and antigen-interaction parts of the binding site of an antibody) coupled covalently to a small chemical scaffold. The report details the actions undertaken by the project, the challenges they faced and their solutions. However, further studies will be required to achieve the ultimate goals of the project, for which the duration of this project was unfortunately too limited.

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