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FP6

Final Report - GENEPI-LOWRT (Genetic Pathways for the Prediction of the Effects of Ionising Radiation: Low Dose Radiosensitivity and Risk to Normal Tissue after Radiotherapy)

Project ID: 36452
Funded under: FP6-SUSTDEV

Abstract

This is the final report for the GENEPI-LOWRT project. The project had two broad aims: firstly, to explore links between the development of severe, normal tissue toxicity following radiotherapy, with transcriptional changes and modulation of gene expression induced at low doses; and secondly, to identify links between individual radiosensitivity and genetic factors. The report concludes that a robust classifier for radiosensitivity to late effects of radiation could not be established due in part to unidentified confounding factors which may contribute to the radiosensitivity, in addition to any genetic contributions.

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Related information

Record Number: 13293 / Last updated on: 2011-11-03
Category: PROJ