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FP6

Scientific Summary- RISC-RAD (DNA damage responses, Genomic instability and Radiation-Induced Cancer: The problem of risk at low and protracted doses)

Project ID: 508842
Funded under: FP6-EURATOM-RADPROT

Abstract

This is the scientific report of the RISC-RAD project funded under the European Commission (EC)'s Sixth Framework Programme (FP6). The research in RISC-RAD was centred around three key questions:

A. Do the processes that drive carcinogenesis due to high dose exposures also contribute to low dose radiation carcinogenesis?
B. To what extent do heritable factors affect individual radiation cancer risks?
C. To translate the information gathered in key questions A and B into practical radiation protection measures - what is the mathematical model for cancer risk estimation that is most consistent with available information and what are the possible operational consequences?

In this scientific summary of RISC-RAD, each of the three key questions are addressed. For clarity KQC is addressed first in Section 2, this provides a summary of some of the key findings and their implications for risk estimation. KQs A and B which deal with the primary scientific issues are covered in Section 3.

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Record Number: 16541 / Last updated on: 2011-04-14
Category: PROJ