Community Research and Development Information Service - CORDIS


Periodic Report - TCMCANCER (Traditional Chinese Medicine in the Post-genomic era: identifying lead therapeutic compounds against cancer)

Project ID: 230232
Funded under: FP7-PEOPLE


This is the periodic report of the TCMCANCER project, which is funded under the European Commission (EC) Seventh Framework Programme (FP7). During the first year of the research, 275 purified compounds originating from Chinese medicinal herbs were tested for cytotoxic effects on several cancer cell lines.

The project identified nine compounds which were subsequently isolated and purified, and their structure determined by nuclear magnetic resonance spectroscopy. From the compounds tested, 22 exhibited medium to high cytotoxic activities in at least one cancer cell line. The identified active compounds, available in suitable amounts for in vivo assays, will be used in mouse models during the last two years of the project to test their anti-cancer and pharmacological properties.

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Record Number: 17073 / Last updated on: 2013-07-05
Category: PROJ