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The report describes the work carried out to establish the correlation between the prothrombin time determined with a new preparation of thromboplastin from rabbit brain and that obtained with the international reference preparation of thromboplastin from human brain origin (coded IRP 67/40). As this original IRP no longer exists, the correlation could not be done directly but was made instead through measurements against CRM 149, the previous certified reference material for rabbit thromboplastin. The final uncertainty of the new thromboplastin is necessarily increased by the uncertainty of the older one. The new rabbit thromboplastin preparation has been shown to be homogeneous and stable.

Additional information

Authors: VAN DEN BESSELAAR A M H P, Academisch Ziekenhuis, Leiden (NL)
Bibliographic Reference: EUR 11686 EN (1988)
Availability: (2)
ISBN: ISBN 92-825-9064-X;CD-NA-
Record Number: 198910045 / Last updated on: 1994-12-01
Original language: en
Available languages: en
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