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Protracted application of 224Ra in NMRI-mice showed two different effects compared to the single application: a) In higher dose ranges the osteosarcoma induction was up to tenfold higher after protracted application compared to single injection. b) In the lowest dose group (18.5 kBq 224Ra injected) an early induction of lymphomas was observed during and shortly after the injection period (36 weeks) in the protracted group.

Additional information

Authors: MÜLLER W A, Gesellschaft für Strahlen- und Umweltforschung mbH München (DE);MULLER W A, Gesellschaft fur Strahlen- und Umweltforschung mbH Munchen (DE)
Bibliographic Reference: Paper presented: Seminar of the Inhalation Toxicology Research Institute, Albuquerque, NM (US), Oct. 10 1988
Availability: Text not available
Record Number: 198910868 / Last updated on: 1994-12-01
Original language: en
Available languages: en
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