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Abstract

Between 1952 and 1980 about 250 patients with ankylosing spondylitis were treated with 224-Ra at the Orthopaedic University Hospital of Frankfurt/M. In 1970, 119 of them were examined and X-rayed as was another group of 40 patients in 1980. The results of those examined could be compared with a group of patients treated without 224-Ra. Patients with 224-Ra demonstrated a long-lasting period of subjective improvement after average. Blood examinations show inflammatory activities. Nevertheless, the ankylosing spondylitis proceeded. In the final stages of the disease, neither the clinical aspects nor the X- rays showed any specific effect due to 224-Ra. Blood examinations, especially blood cells and liver, had shown no specific changes. We observed no case of malignant bone tumor. Of the 169 examined patients, 22 had a total of 32 children after the treatment with 224-Ra. Among these was a set of twins with cerebral palsy and diabetes insipidus renalis. In conclusion, 224-Ra in ankylosing spondylitis is a recommended treatment without higher risk compared to the common therapy with drugs.

Additional information

Authors: SCHMITT E, ORTHOPAEDISCHE UNIVERSITAETSKLINIK FRIEDRICHSHEIM, FRANKFURT (GERMANY);GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG MBH MUENCHEN, NEUHERBERG (GERMANY);RUCKBEIL C, ORTHOPAEDISCHE UNIVERSITAETSKLINIK FRIEDRICHSHEIM, FRANKFURT (GERMANY);GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG MBH MUENCHEN, NEUHERBERG (GERMANY);WICK R R ORTHOPAEDISCHE UNIVERSITAETSKLINIK FRIEDRICHSHEIM, FRANKFURT (GERMANY), ORTHOPAEDISCHE UNIVERSITAETSKLINIK FRIEDRICHSHEIM, FRANKFURT (GERMANY);GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG MBH MUENCHEN, NEUHERBERG (GERMANY);GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG MBH MUENCHEN, NEUHERBERG (GERMANY), ORTHOPAEDISCHE UNIVERSITAETSKLINIK FRIEDRICHSHEIM, FRANKFURT (GERMANY);GESELLSCHAFT FUER STRAHLEN- UND UMWELTFORSCHUNG MBH MUENCHEN, NEUHERBERG (GERMANY)
Bibliographic Reference: HEALTH PHYSICS, VOL. 44 (1983), SUPPLEMENT NO. 1, PP. 197-202
Record Number: 1989122013900 / Last updated on: 1987-01-01
Category: PUBLICATION
Available languages: en