EFECTS OF PRENATAL IRRADIATION WITH SPECIAL EMPHASIS ON LATE EFFECTS
According to our investigations X-ray and nuclear diagnostic radiation exposures generate - with exceptions - fetal doses which, according to the present state of knowledge, do not make a termination necessary. However, as the literature on animal experiments unanimously rejects a so-called threshold dose for fetal damage after irradiation in early pregnancy, and as epidemiological studies in man indicate an increased risk of carcinoma and leukaemia, then as well as for genetic reasons it is definitely necessary to avoid radiation exposure in early pregnancy. More attention should be paid to the rule limiting X-ray examinations of the abdomen and nuclear-medical examinations in women to only the first 10 days after menstruation, in order to avoid the irradiation of unknown pregnancies. As before we recommend termination for fetal exposures of above 100 mGy. At lower radiation exposure a termination should be advised when additional teratogenic noxae are present at the same time. The results of our long-term investigations so far allow the conclusion that one was entitled to recommend no termination for a fetal exposure of below 100 mGy. Furthermore the findings indicate a tendency which raises the question of increasing the dose limit from 100 mGy. But this question has to be discussed at a later time. The "Investigation Programme 1967" is being continued systematically. The authors appreciate any advice about the programme and its methodology.
Bibliographic Reference: EUR 8067 EN (1984) FS, 242 P., BFR 700, EUROFFICE, LUXEMBOURG, POB 1003
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Record Number: 1989122059900 / Last updated on: 1987-01-01
Available languages: en