CHANGES OF THE LYMPHOCYTE POPULATIONS AND THEIR ROLE AS BIOLOGICAL INDICATOR FOR IONIZING RADIATION
Ionizing radiation causes changes of the immune system of mammals including human beings. Within the scope of a research project supported by the Commission of the European Communities that started at the beginning of 1983, it is being examined which of those changes could be useful biological indicators for ionizing radiation. For this purpose peripheral blood of healthy individuals was first irradiated in vitro with different doses. Then absolute numbers and proportions of the lymphocyte subpopulations were determined. Furthermore the formation of antibodies after stimulation with mitogens was investigated. For all the effects dose response relationships were established. Occupationally exposed persons and patients treated with ionizing radiation will have to be included in further studies. This contribution describes the applied methods; the results that could already be obtained, and the further proceeding.
Bibliographic Reference: IRPA-CONGRESS 1984, BERLIN-WEST (GERMANY), MAY 7-12, 1984 WRITE TO CEC LUXEMBOURG, DG XIII/A2, POB 1907 MENTIONING PAPER E 31308
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Record Number: 1989122091900 / Last updated on: 1987-01-01
Available languages: en